细胞重编程与再生生物技术的兴起。

Cellular reprogramming and the rise of rejuvenation biotech.

作者信息

de Magalhães João Pedro, Ocampo Alejandro

机构信息

Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.

Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.

出版信息

Trends Biotechnol. 2022 Jun;40(6):639-642. doi: 10.1016/j.tibtech.2022.01.011. Epub 2022 Feb 18.

DOI:10.1016/j.tibtech.2022.01.011

PMID:35190201

Abstract

Cells can be rejuvenated and biological clocks reset using cellular reprogramming. A growing number of companies now aim to use cellular reprogramming to develop therapies for rejuvenating human beings. Can the 'young' science of rejuvenation, currently mostly based on in vitro studies, drive a new biotech field toward clinical applications?

摘要

通过细胞重编程可以使细胞恢复活力并重置生物钟。现在越来越多的公司旨在利用细胞重编程来开发使人恢复活力的疗法。目前主要基于体外研究的新兴的恢复活力科学能否推动一个新的生物技术领域走向临床应用呢？