Yaron Itay, Melloni Lucia, Pitts Michael, Mudrik Liad
Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
Department of Neurology, New York University Grossman School of Medicine, New York, NY, USA.
Nat Hum Behav. 2022 Apr;6(4):593-604. doi: 10.1038/s41562-021-01284-5. Epub 2022 Feb 21.
Understanding how consciousness arises from neural activity remains one of the biggest challenges for neuroscience. Numerous theories have been proposed in recent years, each gaining independent empirical support. Currently, there is no comprehensive, quantitative and theory-neutral overview of the field that enables an evaluation of how theoretical frameworks interact with empirical research. We provide a bird's eye view of studies that interpreted their findings in light of at least one of four leading neuroscientific theories of consciousness (N = 412 experiments), asking how methodological choices of the researchers might affect the final conclusions. We found that supporting a specific theory can be predicted solely from methodological choices, irrespective of findings. Furthermore, most studies interpret their findings post hoc, rather than a priori testing critical predictions of the theories. Our results highlight challenges for the field and provide researchers with an open-access website ( https://ContrastDB.tau.ac.il ) to further analyse trends in the neuroscience of consciousness.
理解意识如何从神经活动中产生仍然是神经科学面临的最大挑战之一。近年来提出了许多理论,每种理论都获得了独立的实证支持。目前,该领域尚无全面、定量且理论中立的综述,无法对理论框架与实证研究的相互作用进行评估。我们对根据四种主要意识神经科学理论中的至少一种来解释其研究结果的研究进行了全景式观察(N = 412 项实验),探讨研究人员的方法选择可能如何影响最终结论。我们发现,仅从方法选择就可以预测对特定理论的支持,而与研究结果无关。此外,大多数研究都是事后解释其研究结果,而不是对理论的关键预测进行先验检验。我们的结果凸显了该领域面临的挑战,并为研究人员提供了一个开放获取的网站(https://ContrastDB.tau.ac.il),以进一步分析意识神经科学的趋势。