Sattin Davide, Magnani Francesca Giulia, Bartesaghi Laura, Caputo Milena, Fittipaldo Andrea Veronica, Cacciatore Martina, Picozzi Mario, Leonardi Matilde
Neurology, Public Health, Disability Unit-Scientific Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy.
Experimental Medicine and Medical Humanities-PhD Program, Biotechnology and Life Sciences Department and Center for Clinical Ethics, Insubria University, 21100 Varese, Italy.
Brain Sci. 2021 Apr 24;11(5):535. doi: 10.3390/brainsci11050535.
The amount of knowledge on human consciousness has created a multitude of viewpoints and it is difficult to compare and synthesize all the recent scientific perspectives. Indeed, there are many definitions of consciousness and multiple approaches to study the neural correlates of consciousness (NCC). Therefore, the main aim of this article is to collect data on the various theories of consciousness published between 2007-2017 and to synthesize them to provide a general overview of this topic. To describe each theory, we developed a thematic grid called the dimensional model, which qualitatively and quantitatively analyzes how each article, related to one specific theory, debates/analyzes a specific issue. Among the 1130 articles assessed, 85 full texts were included in the prefinal step. Finally, this scoping review analyzed 68 articles that described 29 theories of consciousness. We found heterogeneous perspectives in the theories analyzed. Those with the highest grade of variability are as follows: subjectivity, NCC, and the consciousness/cognitive function. Among sub-cortical structures, thalamus, basal ganglia, and the hippocampus were the most indicated, whereas the cingulate, prefrontal, and temporal areas were the most reported for cortical ones also including the thalamo-cortical system. Moreover, we found several definitions of consciousness and 21 new sub-classifications.
关于人类意识的知识量催生了众多观点,很难对所有最新的科学观点进行比较和综合。事实上,意识有许多定义,研究意识神经关联(NCC)也有多种方法。因此,本文的主要目的是收集2007年至2017年间发表的关于意识的各种理论的数据,并对其进行综合,以提供该主题的总体概述。为了描述每种理论,我们开发了一个名为维度模型的主题网格,该网格定性和定量地分析了每篇与一种特定理论相关的文章如何辩论/分析一个特定问题。在评估的1130篇文章中,85篇全文被纳入最终步骤之前。最后,这项范围综述分析了68篇描述29种意识理论的文章。我们在分析的理论中发现了不同的观点。变异性最高的方面如下:主观性、NCC以及意识/认知功能。在皮层下结构中,丘脑、基底神经节和海马体被提及最多,而扣带回、前额叶和颞叶区域在皮层结构中被报道最多,其中也包括丘脑-皮层系统。此外,我们发现了几种意识的定义和21种新的子分类。