[Not Available].
作者信息
Güttler Thomas, Dobbelstein Matthias, Görlich Dirk
机构信息
Max-Planck-Institut für Multidisziplinäre Naturwissenschaften, Am Fassberg 11, D-37077 Göttingen, Deutschland.
Institut für molekulare Onkologie, Universitätsmedizin Göttingen, Justus-von-Liebig-Weg 11, D-37077 Göttingen, Deutschland.
出版信息
Biospektrum (Heidelb). 2022;28(1):39-42. doi: 10.1007/s12268-022-1684-y. Epub 2022 Feb 13.
Abstract
Monoclonal immunoglobulins are widely successful as therapeutics and have also been effective in treating COVID-19. However, their production in mammalian cells is expensive and cannot be scaled to meet the demand in a global pandemic. Camelid VH antibodies (also called nanobodies), however, can be manufactured cost-efficiently in bacteria or yeast. Here we highlight our progress in developing nanobodies that effectively neutralize SARS-CoV-2 and its variants.
摘要
相似文献
1
[Not Available].
Biospektrum (Heidelb). 2022;28(1):39-42. doi: 10.1007/s12268-022-1684-y. Epub 2022 Feb 13.
2
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