Department of Statistics, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
PLoS One. 2022 Feb 23;17(2):e0264229. doi: 10.1371/journal.pone.0264229. eCollection 2022.
One of the most important applications of statistical analysis is in health research and applications. Cancer studies are mostly required special statistical considerations in order to find the appropriate model for fitting the survival data. Existing classical distributions rarely fit such data well and an increasing interest has been shown recently in developing more flexible distributions by introducing some additional parameters to the basic model. In this paper, a new five-parameters distribution referred as alpha power Kumaraswamy Weibull distribution is introduced and studied. Particularly, this distribution extends the Weibull distribution based on a novel technique that combines two well known generalisation methods, namely, alpha power and T-X transformations. Different characteristics of the proposed distribution, including moments, quantiles, Rényi entropy and order statistics are obtained. The method of maximum likelihood is applied in order to estimate the model parameters based on complete and censored data. The performance of these estimators are examined via conducting some simulation studies. The potential importance and applicability of the proposed distribution is illustrated empirically by means of six datasets that describe the survival of some cancer patients. The results of the analysis indicated to the promising performance of the alpha power Kumaraswamy Weibull distribution in practice comparing to some other competing distributions.
统计分析的一个最重要的应用领域是健康研究和应用。癌症研究通常需要特殊的统计考虑,以便为生存数据找到合适的模型。现有的经典分布很少能很好地拟合此类数据,最近人们越来越感兴趣的是通过向基本模型引入一些附加参数来开发更灵活的分布。本文介绍并研究了一种新的五参数分布,称为 alpha power Kumaraswamy Weibull 分布。特别是,该分布基于一种新颖的技术扩展了 Weibull 分布,该技术结合了两种著名的推广方法,即 alpha power 和 T-X 变换。获得了该分布的不同特征,包括矩、分位数、Renyi 熵和顺序统计量。基于完整数据和删失数据,应用最大似然法估计模型参数。通过进行一些模拟研究,检查了这些估计量的性能。通过描述一些癌症患者生存情况的六个数据集,从实证角度说明了所提出分布的潜在重要性和适用性。分析结果表明,与其他一些竞争分布相比,alpha power Kumaraswamy Weibull 分布在实践中具有很好的性能。