College of Animal Science and Technology, Hunan Agricultural University, Ministry of Education Engineering Research Center of Feed Safety and Efficient Use, Hunan Engineering Research Center of Poultry Production Safety, Hunan Co-Innovation Center of Animal Production Safety, Changsha, 410128, China.
College of Animal Science and Technology, Hunan Agricultural University, Ministry of Education Engineering Research Center of Feed Safety and Efficient Use, Hunan Engineering Research Center of Poultry Production Safety, Hunan Co-Innovation Center of Animal Production Safety, Changsha, 410128, China.
Poult Sci. 2022 Apr;101(4):101722. doi: 10.1016/j.psj.2022.101722. Epub 2022 Jan 13.
The aim of the present study was to evaluate the effect of magnolol (MAG) on growth performance, meat quality, oxidative capacity, and intestinal microbiota in the yellow-feather broilers. A total of 360 one-day-old male yellow-feather broiler chicks were allocated into 5 groups of 6 replicates and 12 chickens per replicate, were fed a basal diet supplemented with 0 (Control group, CON), 100, 200, 300, or 400 mg/kg MAG for 51 d. The results showed that dietary supplementation with 200 and 300 mg/kg MAG increased the average daily gain (ADG) but decreased feed to gain ratio (F/G) during the overall periods (P < 0.05). Dietary MAG increased significantly the redness value (a) of the breast muscle (P < 0.05), and decreased the water loss rate and shear force of the breast meat (P < 0.05). MAG supplement reduced the malondialdehyde (MDA) levels, and increased the glutathione (GSH), superoxide dismutase (SOD), and total antioxidant capacity (T-AOC) levels in breast muscle and jejunum. PCR analysis showed that MAG increased the levels of NF-E2-related factor 2 (Nrf2), NAD(P)H/quinone oxidoreductase 1 (NQO1), heme oxygenase-1 (HO-1), glutathione-S transferase (GST), glutamate-cysteine ligase catalytic subunit (GCLC), glutamate-cysteine ligase modifier subunit (GCLM), and SOD expressions (P < 0.05). Analysis of differential enrichment of gut microbiota found that Faecalibacterium in the cecum of MAG supplemented broilers increased, and Coprobacillus has decreased (P < 0.05). In conclusion, MAG improved growth performance, meat quality of the broilers and antioxidant capacity, and modulated gut microbiota homeostasis.
本研究旨在评估厚朴酚（MAG）对黄羽肉鸡生长性能、肉质、氧化应激和肠道微生物群的影响。将 360 只 1 日龄雄性黄羽肉鸡随机分为 5 组，每组 6 个重复，每个重复 12 只鸡，分别饲喂基础日粮和添加 0（对照组，CON）、100、200、300 或 400 mg/kg MAG 的日粮，试验期 51 d。结果表明，日粮添加 200 和 300 mg/kg MAG 提高了整个试验期的平均日增重（ADG），降低了料重比（F/G）（P < 0.05）。日粮 MAG 显著提高了胸肌的红度值（a）（P < 0.05），降低了胸肉的失水率和剪切力（P < 0.05）。MAG 补充剂降低了胸肌和空肠的丙二醛（MDA）水平，增加了谷胱甘肽（GSH）、超氧化物歧化酶（SOD）和总抗氧化能力（T-AOC）水平。PCR 分析表明，MAG 增加了核因子 E2 相关因子 2（Nrf2）、NAD(P)H/醌氧化还原酶 1（NQO1）、血红素加氧酶-1（HO-1）、谷胱甘肽-S-转移酶（GST）、谷氨酸-半胱氨酸连接酶催化亚基（GCLC）、谷氨酸-半胱氨酸连接酶修饰亚基（GCLM）和 SOD 的表达（P < 0.05）。肠道微生物群差异富集分析发现，添加 MAG 的肉鸡盲肠中产丁酸菌 Faecalibacterium 增加，Coprobacillus 减少（P < 0.05）。综上所述，MAG 改善了肉鸡的生长性能、肉质和抗氧化能力，并调节了肠道微生物群的平衡。
