Department of Paediatrics and Child Health, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa.
Brooklyn Chest Hospital, Cape Town, South Africa.
Int J Tuberc Lung Dis. 2022 Mar 1;26(3):217-223. doi: 10.5588/ijtld.21.0538.
Brooklyn Chest Hospital (BCH) is a specialised TB hospital in Cape Town, South Africa. We describe reasons for admission, patient profiles and hospital-discharge outcomes in children admitted to BCH. This was compared to a previous study (2000-2001). This retrospective, descriptive study included all children (0-14 years) admitted to BCH from January 2016 to December 2017. Data collected from patient folders and a laboratory database included demographic data, reasons for admission, clinical data and hospital outcomes. Of 263 children admitted, 133 (50.6%) were male. The median age was 32 months (IQR 15-75); 48 (18.3%) were HIV-positive and 150 (57.0%) had bacteriologically confirmed TB. Reasons for admission included social/caregiver-related ( = 119, 45.2%), drug-resistant TB ( = 114, 43.3%), TB meningitis ( = 86, 32.7%) and other severe types of TB ( = 63, 24.0%); 110 (41.8%) children had >1 reason for admission. TB meningitis admissions decreased ( = 0.014) and those for drug-resistant TB increased ( < 0.001) compared to 2000-2001. Pulmonary TB was diagnosed in 234 (89.0%), extrapulmonary TB in 149 (56.7%) and 126 (47.9%) had both. At discharge, 73 (27.8%) had completed treatment, 182 (69.2%) were transferred out to complete treatment at community clinics, and 6 (2.3%) died. Although most children were admitted for clinical reasons, social/caregiver-related reasons were also important.
布鲁克林胸医院（BCH）是南非开普敦的一家专门治疗结核病的医院。我们描述了收治到 BCH 的儿童的入院原因、患者特征和出院结局，并与之前的一项研究（2000-2001 年）进行了比较。这项回顾性描述性研究纳入了 2016 年 1 月至 2017 年 12 月期间收治到 BCH 的所有儿童（0-14 岁）。从患者病历和实验室数据库中收集的数据包括人口统计学数据、入院原因、临床数据和医院结局。在 263 名入院的儿童中，133 名（50.6%）为男性。中位数年龄为 32 个月（IQR 15-75）；48 名（18.3%）HIV 阳性，150 名（57.0%）有细菌学确诊的结核病。入院原因包括社会/照护者相关（=119，45.2%）、耐多药结核病（=114，43.3%）、结核性脑膜炎（=86，32.7%）和其他严重类型的结核病（=63，24.0%）；110 名（41.8%）儿童有≥1 个入院原因。与 2000-2001 年相比，结核性脑膜炎入院人数减少（=0.014），耐多药结核病入院人数增加（<0.001）。234 名（89.0%）诊断为肺结核，149 名（56.7%）诊断为肺外结核，126 名（47.9%）同时患有肺结核和肺外结核。出院时，73 名（27.8%）完成治疗，182 名（69.2%）转至社区诊所完成治疗，6 名（2.3%）死亡。尽管大多数儿童因临床原因入院，但社会/照护者相关原因也很重要。
