Vanderhoven C, Douet M, Mitchell K, Page Y, Girard J P
J Immunopharmacol. 1986;8(1):117-23. doi: 10.3109/08923978609031089.
This phase I study demonstrates the immunostimulating properties of SLO4 administered by the oral route in the healthy volunteer. Responses to the test of DTH (delayed type hypersensitivity) were enhanced by SLO4 and the production of MIF (migration inhibiting factor) involved in this response was stimulated. These properties could be correlated with the previously demonstrated induction of interferon by SLO4.
这项I期研究证明了口服SLO4在健康志愿者中的免疫刺激特性。SLO4增强了对迟发型超敏反应(DTH)试验的反应,并刺激了参与该反应的迁移抑制因子(MIF)的产生。这些特性可能与之前证明的SLO4诱导干扰素有关。