Alammari Raghad K, Alhessan Alanoud A, Alturki Abdulaziz A, Aburowais Safa A, Alsharif Mansour H, Alshehri Feras H, Hakami Feddah M, Alsubaie Thawab M, Alhamed Sukaina A, Alsobhi Mosab A, Alshaqaqiq Hussain A, Alshaqaqiq Ali I, Alkharraz Abdullah H, Alhudhayf Ali M, Al-Hawaj Faisal
Medicine, Almaarefa University, Riyadh, SAU.
Medicine, Arabian Gulf University, Manama, BHR.
Cureus. 2022 Jan 19;14(1):e21400. doi: 10.7759/cureus.21400. eCollection 2022 Jan.
Gallbladder disease is a very common condition that encompasses a heterogeneous group of diseases with a wide range of severity and clinical manifestations. Gallbladder disorders include biliary colic, acute cholecystitis, chronic cholecystitis, choledocholithiasis, Mirizzi syndrome, and gallstone ileus. We report the case of a 70-year-old man who presented to the emergency department complaining of worsening abdominal pain, located in the right upper quadrant and radiating to the right shoulder. It was aggravated by food intake and relieved with the use of antacid medications. The medical history of the patient was significant for stable angina, hypertension, diabetes mellitus, hyperlipidemia, and sickle cell trait. Examination of the abdomen revealed generalized tenderness with guarding. Abdominal computed tomography scan demonstrated the presence of significant diffuse thickening of the gallbladder wall with poor contrast enhancement. Complete resection of the gallbladder was performed because of suspected gallbladder carcinoma. Histopathological examination revealed xanthogranulomatous cholecystitis, which is a rare form of chronic cholecystitis. The differentiation between gallbladder carcinoma and xanthogranulomatous cholecystitis may not be easy and histopathological examination is the most accurate way to make the diagnosis.
胆囊疾病是一种非常常见的病症，涵盖了一组异质性疾病，其严重程度和临床表现范围广泛。胆囊疾病包括胆绞痛、急性胆囊炎、慢性胆囊炎、胆总管结石、Mirizzi综合征和胆石性肠梗阻。我们报告一例70岁男性病例，该患者因右上腹疼痛加重并放射至右肩部而到急诊科就诊。进食会使其加重，使用抗酸药物后缓解。患者的病史包括稳定型心绞痛、高血压、糖尿病、高脂血症和镰状细胞性状。腹部检查发现全腹压痛伴肌紧张。腹部计算机断层扫描显示胆囊壁明显弥漫性增厚，增强扫描强化不佳。由于怀疑胆囊癌，遂行胆囊全切术。组织病理学检查显示为黄色肉芽肿性胆囊炎，这是一种罕见的慢性胆囊炎形式。胆囊癌与黄色肉芽肿性胆囊炎的鉴别可能并不容易，组织病理学检查是做出诊断的最准确方法。
