Kidron Ariel, Daahir Christian
Emergency Medicine, Nova Southeastern University Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
Anesthesiology, Aventura Hospital and Medical Center, Aventura, USA.
Cureus. 2022 Jan 19;14(1):e21423. doi: 10.7759/cureus.21423. eCollection 2022 Jan.
Thromboangiitis obliterans (TAO) is an autoimmune vasculitis that typically presents in male smokers between the ages of 25 and 40. Although TAO primarily affects medium-sized blood vessels, it can also infiltrate small blood vessels as well as nerves and veins. The inflammation can cause segmental thrombosing and occlusion of the blood vessels leading to gangrene and eventual amputations. This case presents a unique sequela of TAO, in which a 28-year-old male with a chronic tobacco smoking history was diagnosed with TAO after presenting with pain and discoloration in his foot, in addition to superimposed osteomyelitis. This case serves to remind emergency clinicians, internal medicine physicians, general practitioners, and infectious disease specialists of the TAO differential in patients presenting with pain and discoloration in the feet, as well as the importance of working up the patient for any superimposed infections.
血栓闭塞性脉管炎（TAO）是一种自身免疫性血管炎，通常见于年龄在25至40岁之间的男性吸烟者。虽然TAO主要影响中等大小的血管，但它也可累及小血管以及神经和静脉。炎症可导致血管节段性血栓形成和闭塞，从而导致坏疽并最终截肢。本病例呈现了TAO的一种独特后遗症，一名有长期吸烟史的28岁男性，在出现足部疼痛和变色以及并发骨髓炎后被诊断为TAO。该病例提醒急诊临床医生、内科医生、全科医生和传染病专家，对于出现足部疼痛和变色的患者要考虑到TAO的鉴别诊断，以及对患者进行任何并发感染检查的重要性。
