Rijal Swarup Sharma, Oke Ibiyemi, Shrestha Biraj
Internal Medicine, Tower Health Medical Group, Wyomissing, USA.
Cureus. 2022 Jan 19;14(1):e21427. doi: 10.7759/cureus.21427. eCollection 2022 Jan.
Lithium has been widely used as a mood stabilizer. With its narrow therapeutic index, systemic side effects, primarily neurological are a concern. Cardiotoxic effects of lithium are rare, reported as non-specific T-wave flattening, prolonged QT interval, sinus node dysfunction, ventricular tachycardia, cardiomyopathy, and myocardial infarction. We report an interesting case of a young female patient with schizoaffective disorder on lithium who developed life-threatening cardiotoxicity secondary to lithium requiring urgent dialysis.
锂已被广泛用作情绪稳定剂。由于其治疗指数狭窄,全身性副作用(主要是神经系统副作用)令人担忧。锂的心脏毒性作用罕见,表现为非特异性T波低平、QT间期延长、窦房结功能障碍、室性心动过速、心肌病和心肌梗死。我们报告了一例有趣的病例,一名患有分裂情感障碍的年轻女性患者在服用锂剂时出现了危及生命的锂继发性心脏毒性,需要紧急透析。