Department of Psychiatry, Nepalgunj Medical College Teaching Hospital, Kohalpur, Banke, Nepal.
Department of Pediatrics, Nepalgunj Medical College Teaching Hospital, Kohalpur, Banke, Nepal.
JNMA J Nepal Med Assoc. 2021 Oct 15;59(242):979-982. doi: 10.31729/jnma.6907.
Dementia is a chronic and progressive syndrome due to disease of brain. Alzhemeir's disease is the most common cause of dementia. There are very few studies regarding prevalence of dementia in Nepal. The objective of this study is to find the prevalence of dementia in 50 years and older patients from the psychiatry out patient department of a tertiary care center.
A descriptive cross-sectional study was done in patients attending to psychiatry outpatient department over one year from May 2020 to April 2021. Ethical approval was taken from the Institutional Review Committee (Reference number: 745/077-078). The data were assessed using Statistical Package for Social Sciences version 20. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data.
Out of 1332 patients, 52 (3.9%) (95% Confidence Interval=2.86-4.93) patients had dementia in which 30 (57.7%) are male while 22 (42.3%) are female. Mean age of study population is 70.12±11.21 with age range of 50 years to 88 years. We found 29 (55.8%) moderate, 18 (34.6%) severe and 5 (9.6%) mild type of dementia. We had 34 (65.3%) Alzheimer's followed by 16 (30.8%) vascular and 2 (3.9%) others types of dementia.
This study concludes that the prevalence of dementia in 50 years and older patients is similar in comparison to other studies done in similar settings.
痴呆是一种由于脑部疾病引起的慢性、进行性综合征。阿尔茨海默病是痴呆最常见的原因。关于尼泊尔痴呆的患病率，研究甚少。本研究的目的是在一家三级护理中心的精神科门诊患者中发现 50 岁及以上患者的痴呆患病率。
这是一项在 2020 年 5 月至 2021 年 4 月期间的一年时间内，对精神科门诊患者进行的描述性横断面研究。本研究已获得机构审查委员会的伦理批准（编号：745/077-078）。使用社会科学统计软件包 20 版评估数据。计算了 95%置信区间的点估计值以及二项数据的频率和比例。
在 1332 名患者中，有 52 名（3.9%）（95%置信区间=2.86-4.93）患者患有痴呆，其中 30 名（57.7%）为男性，22 名（42.3%）为女性。研究人群的平均年龄为 70.12±11.21 岁，年龄范围为 50 岁至 88 岁。我们发现 29 名（55.8%）为中度，18 名（34.6%）为重度，5 名（9.6%）为轻度痴呆。我们有 34 名（65.3%）阿尔茨海默病，其次是 16 名（30.8%）血管性痴呆和 2 名（3.9%）其他类型的痴呆。
本研究得出的结论是，与在类似环境中进行的其他研究相比，50 岁及以上患者的痴呆患病率相似。
