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尿液碘含量不足的中学生:一项描述性横断面研究。

Insufficient Iodine Level in Urine among Children of a Secondary School: A Descriptive Cross-sectional Study.

机构信息

Public Health and Infectious Disease Research Center, Kathmandu, Nepal.

Central Department of Microbiology, Tribhuvan University, Kirtipur, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2021 Oct 15;59(242):1026-1029. doi: 10.31729/jnma.6084.

Abstract

Introduction: Iodine deficiency disorders are common endocrinopathies in Nepal. Children are at risk for iodine deficiency disorders. Irreversible mental retardation and brain damage in children are the devastating disorders lead by iodine deficiency. Therefore, the main objective of the study was to find out the prevalence of insufficient iodine level among the children of a secondary school. Methods: This descriptive cross-sectional study was conducted in urine from April 2019 to July 2019 after obtaining ethical approval from Nepal Health Research Council (Registration number: 802/2018). Forty-six urine samples were collected from school children for iodine estimation. Convenience sampling was done. Data were entered into Statistical Package for the Social Science version 21 and descriptive analyses were done. Point estimate at 95% confidence interval was calculated along with frequency and proportion for binary data. Results: Among the 46 students, majority 36 (78.30%) (95% Confidence Interval= 66.30-90.21) of the school children had insufficient urine iodine level. Among 36 salt samples collected from school children with low urine iodine level, 8 (22.2%) salt samples had iodine less than 15ppm. Conclusions: Iodine estimation revealed a very high percentage of urine samples containing insufficient levels of iodine is similar as compared to studies done in similar settings. Hence, the school children were at risk of iodine deficiency disorders. Iodine deficiency disorders prevention programs should be priority intervention based on available evidence.

摘要

简介

碘缺乏症是尼泊尔常见的内分泌疾病。儿童面临碘缺乏症的风险。儿童碘缺乏症会导致不可逆转的智力迟钝和脑损伤。因此,本研究的主要目的是了解一所中学儿童碘水平不足的发生率。

方法

这是一项描述性的横断面研究,于 2019 年 4 月至 7 月在获得尼泊尔健康研究委员会(注册号:802/2018)的伦理批准后,从尿液中进行。从学校儿童中采集了 46 份尿液样本进行碘测定。采用便利抽样法。将数据输入社会科学统计软件包 21 版,并进行描述性分析。计算了 95%置信区间的点估计值,以及二进制数据的频率和比例。

结果

在 46 名学生中,36 名(78.30%)(95%置信区间=66.30-90.21)的学生尿液碘水平不足。在 36 份来自碘水平低的学生的盐样本中,有 8 份(22.2%)盐样本的碘含量低于 15ppm。

结论

碘测定结果显示,大量(78.30%)学生的尿液样本中含有不足的碘,与在类似环境中进行的研究相似。因此,这些学生面临碘缺乏症的风险。根据现有证据,应优先考虑针对碘缺乏症的预防计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ff2/9107819/9f2cade7c8ee/JNMA-59-242-1026-g1.jpg

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