National Medical College and Teaching Hospital.
Department of Pathology, National Medical College and Teaching Hospital, Birgunj, Nepal.
JNMA J Nepal Med Assoc. 2021 Nov 15;59(243):1177-1179. doi: 10.31729/jnma.6709.
Actinomyces are a part of the normal flora of the cervicofacial region, gastrointestinal tract, and urogenital tract, but can cause infections when the normal mucosal barrier is lost. Herein, we report a rare case of actinomycosis of the gallbladder in a 60-years-old-female. The patient presented with right hypochondrium pain since three months; ultrasonography showed cholelithiasis with thick oedematous wall. An open cholecystectomy was carried out. Histological examination revealed an inflamed gallbladder with colonies of radiating filamentous structures having numerous sulphur granules which on gram staining showed filamentous gram-positive rods. The diagnosis of Actinomycosis of gallbladder was made. After cholecystectomy, prolonged antimicrobial therapy is recommended for patient with actinomycosis to prevent recurrence and even mortality.
放线菌是颈面部、胃肠道和泌尿生殖道正常菌群的一部分，但当正常黏膜屏障丧失时，可引起感染。本文报道了一例罕见的女性胆囊放线菌病。患者 60 岁，因右侧季肋部疼痛 3 个月就诊；超声检查提示胆石症伴厚壁水肿。行开腹胆囊切除术。组织学检查显示胆囊炎症，放射状丝状结构的菌落，有许多硫磺颗粒，革兰氏染色显示丝状革兰氏阳性杆菌。诊断为胆囊放线菌病。胆囊切除术后，建议对放线菌病患者进行长期抗菌治疗，以预防复发甚至死亡。
