Digestive Disease Center, Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, China.
Department of Gastrointestinal Surgery, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
Curr Oncol. 2022 Feb 17;29(2):1201-1212. doi: 10.3390/curroncol29020102.
The effect of multidisciplinary team intervention (MDT) on the prognosis of advanced gastric cancer (GC) is still controversial. This study aims to analyze the effect of MDTs on the overall survival time of advanced gastric cancer patients.
Patients with advanced GC who underwent surgical treatment between 2007 and 2014 were included in the study. They were divided into two groups; the MDT group received MDT treatment and the non-MDT group received conventional treatment. The Kaplan-Meier method was used to compare the overall survival (OS) of the two groups. The prognostic factors of advanced GC were evaluated by multivariate Cox regression analysis.
394 patients were included in our study. Kaplan-Meier survival analysis showed that the prognosis of advanced GC patients with who underwent MDT intervention was better than those without (3-year OS of 55.6% vs. 46.1%, = 0.005), Multivariate analysis indicated that MDT intervention could reduce mortality (HR = 0.493, < 0.001).
MDT intervention is an effective measure that improves the survival of patients with advanced GC.
多学科团队干预（MDT）对晚期胃癌（GC）预后的影响仍存在争议。本研究旨在分析 MDT 对晚期胃癌患者总生存时间的影响。
纳入 2007 年至 2014 年间接受手术治疗的晚期 GC 患者。将其分为 MDT 组和非 MDT 组，MDT 组接受 MDT 治疗，非 MDT 组接受常规治疗。采用 Kaplan-Meier 法比较两组的总生存期（OS）。采用多因素 Cox 回归分析评估晚期 GC 的预后因素。
共纳入 394 例患者。Kaplan-Meier 生存分析显示，接受 MDT 干预的晚期 GC 患者的预后优于未接受 MDT 干预的患者（3 年 OS：55.6%比 46.1%， = 0.005）。多因素分析表明，MDT 干预可降低死亡率（HR = 0.493， < 0.001）。
MDT 干预是改善晚期 GC 患者生存的有效措施。
