三图像脑部正电子发射断层显像（PET）系统的蒙特卡罗特性描述

Monte Carlo Characterization of the Trimage Brain PET System.

作者信息

Masturzo Luigi, Carra Pietro, Erba Paola Anna, Morrocchi Matteo, Pilleri Alessandro, Sportelli Giancarlo, Belcari Nicola

机构信息

Department of Physics "E. Fermi", University of Pisa, 56127 Pisa, Italy.

National Institute of Nuclear Physics (INFN), Pisa Section, 56127 Pisa, Italy.

出版信息

J Imaging. 2022 Jan 23;8(2):21. doi: 10.3390/jimaging8020021.

DOI:10.3390/jimaging8020021

PMID:35200724

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8878795/

Abstract

The TRIMAGE project aims to develop a brain-dedicated PET/MR/EEG (Positron Emission Tomography/Magnetic Resonance/Electroencephalogram) system that is able to perform simultaneous PET, MR and EEG acquisitions. The PET component consists of a full ring with 18 sectors. Each sector includes three square detector modules based on dual sstaggered LYSO:Ce matrices read out by SiPMs. Using Monte Carlo simulations and following NEMA (National Electrical Manufacturers Association) guidelines, image quality procedures have been applied to evaluate the performance of the PET component of the system. The performance are reported in terms of spatial resolution, uniformity, recovery coefficient, spill over ratio, noise equivalent count rate (NECR) and scatter fraction. The results show that the TRIMAGE system is at the top of the current brain PET technologies.

摘要

TRIMAGE项目旨在开发一种专门用于脑部的PET/MR/EEG（正电子发射断层扫描/磁共振成像/脑电图）系统，该系统能够同时进行PET、MR和EEG采集。PET组件由一个带有18个扇区的全环组成。每个扇区包括三个基于双交错LYSO:Ce矩阵的方形探测器模块，由硅光电倍增管读出。利用蒙特卡罗模拟并遵循美国国家电气制造商协会（NEMA）的指导方针，已应用图像质量程序来评估该系统PET组件的性能。性能报告包括空间分辨率、均匀性、恢复系数、溢出率、噪声等效计数率（NECR）和散射分数。结果表明，TRIMAGE系统在当前脑部PET技术中处于领先地位。