Secchi A, Pontiroli A E, Cammelli L, Bizzi A, Cini M, Pozza G
Klin Wochenschr. 1986 Mar 17;64(6):265-9. doi: 10.1007/BF01711933.
The present study was aimed to investigate the metabolic effects of acute and chronic oral administration of maltitol (4-O-i-D-glucopyranosyl-D-glucitol), a hypocaloric sweetener obtained from maltose by catalytic hydrogenation. Fifty grams of maltitol induced a increase lower glycemic and insulinemic than the same dose of glucose or sucrose. No variations of plasma glucose and serum insulin levels were observed after 180 min. A slight increase of plasma maltitol was observed 45 min after maltitol. The chronic administration of maltitol (10 g 3 X daily for 5 days) induced no variations of glycemia or insulinemia when compared with the same dose of sucrose. Plasma sorbitol levels were slightly higher after maltitol than after sucrose. Low amounts of maltitol were detected in the urine and feces.
本研究旨在调查急性和慢性口服麦芽糖醇（4-O-α-D-吡喃葡萄糖基-D-葡萄糖醇）的代谢效应，麦芽糖醇是一种通过催化氢化从麦芽糖中获得的低热量甜味剂。50克麦芽糖醇引起的血糖和胰岛素水平升高低于相同剂量的葡萄糖或蔗糖。180分钟后未观察到血浆葡萄糖和血清胰岛素水平的变化。服用麦芽糖醇45分钟后，血浆麦芽糖醇略有增加。与相同剂量的蔗糖相比，慢性服用麦芽糖醇（每天3次，每次10克，共5天）不会引起血糖或胰岛素血症的变化。麦芽糖醇后的血浆山梨醇水平略高于蔗糖后。在尿液和粪便中检测到少量麦芽糖醇。
