Department of Orthopaedic Surgery, The Permanente Medical Group, 2nd Floor, 1600 Owens St, San Francisco, CA, 94158, USA.
Surgical Outcomes and Analysis, Kaiser Permanente, San Diego, CA, USA.
Knee Surg Sports Traumatol Arthrosc. 2022 Oct;30(10):3311-3321. doi: 10.1007/s00167-022-06912-9. Epub 2022 Feb 24.
(1) Report concomitant cartilage and meniscal injury at the time of anterior cruciate ligament reconstruction (ACLR), (2) evaluate the risk of aseptic revision ACLR during follow-up, and (3) evaluate the risk of aseptic ipsilateral reoperation during follow-up.
Using a United States integrated healthcare system's ACLR registry, patients who underwent primary isolated ACLR were identified (2010-2018). Multivariable Cox proportional-hazards regression was used to evaluate the risk of aseptic revision, with a secondary outcome evaluating ipsilateral aseptic reoperation. Outcomes were evaluated by time from injury to ACLR: acute (< 3 weeks), subacute (3 weeks-3 months), delayed (3-9 months), and chronic (≥ 9 months).
The final sample included 270 acute (< 3 weeks), 5971 subacute (3 weeks-3 months), 5959 delayed (3-9 months), and 3595 chronic (≥ 9 months) ACLR. Medial meniscus [55.4% (1990/3595 chronic) vs 38.9% (105/270 acute)] and chondral injuries [40.0% (1437/3595 chronic) vs 24.8% (67/270 acute)] at the time of ACLR were more common in the chronic versus acute groups. The crude 6-year revision rate was 12.9% for acute ACLR, 7.0% for subacute, 5.1% for delayed, and 4.4% for chronic ACLR; reoperation rates a 6-year follow-up was 15.0% for acute ACLR, 9.6% for subacute, 6.4% for delayed, and 8.1% for chronic ACLR. After adjustment for covariates, acute and subacute ACLR had higher risks for aseptic revision (acute HR 1.70, 95% CI 1.07-2.72, p = 0.026; subacute HR 1.25, 95% CI 1.01-1.55, p = 0.040) and aseptic reoperation (acute HR 2.04, 95% CI 1.43-2.91, p < 0.001; subacute HR 1.31, 95% CI 1.11-1.54, p = 0.002) when compared to chronic ACLR.
In this cohort study, while more meniscal and chondral injuries were reported for ACLR performed ≥ 9 months after the date of injury, a lower risk of revision and reoperation was observed following chronic ACLR relative to patients undergoing surgery in acute or subacute fashions.
(1)报告前交叉韧带重建术(ACLR)时伴随的软骨和半月板损伤,(2)评估随访期间发生无菌性翻修 ACLR 的风险,(3)评估随访期间同侧无菌性再次手术的风险。
使用美国综合医疗保健系统的 ACLR 登记处,确定了接受初次单纯 ACLR 的患者(2010-2018 年)。多变量 Cox 比例风险回归用于评估无菌性翻修的风险,次要结局评估同侧无菌性再手术。结果通过从损伤到 ACLR 的时间进行评估:急性(<3 周)、亚急性(3 周-3 个月)、延迟(3-9 个月)和慢性(≥9 个月)。
最终样本包括 270 例急性(<3 周)、5971 例亚急性(3 周-3 个月)、5959 例延迟(3-9 个月)和 3595 例慢性(≥9 个月)ACLR。慢性 ACLR 时的内侧半月板[55.4%(1990/3595 例慢性)比急性 ACLR 的 38.9%(67/270 例急性)]和软骨损伤[40.0%(1437/3595 例慢性)比急性 ACLR 的 24.8%(67/270 例急性)]更常见。急性 ACLR 的 6 年翻修率为 12.9%,亚急性为 7.0%,延迟为 5.1%,慢性为 4.4%;6 年随访时的再手术率为急性 ACLR 的 15.0%,亚急性为 9.6%,延迟为 6.4%,慢性为 8.1%。在调整了协变量后,急性和亚急性 ACLR 发生无菌性翻修的风险更高(急性 HR 1.70,95%CI 1.07-2.72,p=0.026;亚急性 HR 1.25,95%CI 1.01-1.55,p=0.040)和无菌性再手术(急性 HR 2.04,95%CI 1.43-2.91,p<0.001;亚急性 HR 1.31,95%CI 1.11-1.54,p=0.002)与慢性 ACLR 相比。
在这项队列研究中,尽管在受伤后≥9 个月进行 ACLR 时报告了更多的半月板和软骨损伤,但与急性或亚急性手术相比,慢性 ACLR 后翻修和再手术的风险较低。