Wu Yi, Dai Yeqin, Wang Tao, Jin Hong, Peng Jianzhong, Xu Ai'er
Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang Province, China.
Dermatol Ther. 2022 May;35(5):e15400. doi: 10.1111/dth.15400. Epub 2022 Feb 27.
Leukotrichia is one of the difficulties of vitiligo treatment. Hair follicle transplantation is an efficient method to treat vitiligo-associated leukotrichia. A trichiasis electrolyzer, commonly used for treating trichiasis, can be used to damage and remove the depigmented hair follicles. To evaluate the efficacy of the electrolysis of depigmented hair using a trichiasis electrolyzer combined with single hair follicle transplantation for the treatment of vitiligo-associated leukotrichia. A total of 15 patients with stable vitiligo-associated eyebrow and eyelash leukotrichia were enrolled from Department of Dermatology, Hangzhou Third People's Hospital between January 2020 and January 2021. All patients were treated using a trichiasis electrolyzer combined with single hair follicle transplantation. The patients were followed up at the first week, the first month, the third month, and the sixth month after surgery. The texture and growth state of the transplanted hair were observed, and the number of surviving transplanted follicles and regenerating depigmented follicles were recorded. The transplanted hair grew as expected with natural shape. No local infection or obvious scar was observed. Most of the depigmented hair in the lesion area re-pigmented and only a few depigmented hairs regenerated. The average survival rate of the transplanted hair follicles was 71.6%, and the average regeneration rate of the depigmented hair was 11.6%. The electrolysis of depigmented hair using a trichiasis electrolyzer combined with single hair follicle transplantation was an effective and safe method to treat vitiligo-associated leukotrichia.
白发症是白癜风治疗的难点之一。毛囊移植是治疗白癜风相关白发症的一种有效方法。一种常用于治疗倒睫的倒睫电解器可用于破坏和去除色素脱失的毛囊。为评估使用倒睫电解器联合单毛囊移植电解色素脱失毛发治疗白癜风相关白发症的疗效。2020年1月至2021年1月期间，从杭州市第三人民医院皮肤科招募了15例稳定期白癜风相关眉部和睫毛白发症患者。所有患者均采用倒睫电解器联合单毛囊移植进行治疗。术后第1周、第1个月、第3个月和第6个月对患者进行随访。观察移植毛发的质地和生长状态，记录存活移植毛囊和再生色素脱失毛囊的数量。移植毛发按预期生长，形态自然。未观察到局部感染或明显瘢痕。病变区域大部分色素脱失毛发重新色素沉着，仅少数色素脱失毛发再生。移植毛囊平均成活率为71.6%，色素脱失毛发平均再生率为11.6%。使用倒睫电解器联合单毛囊移植电解色素脱失毛发是治疗白癜风相关白发症的一种有效且安全的方法。
