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辛普森悖论及其对列联表理论的其他贡献的量化。

The quantification of Simpson's paradox and other contributions to contingency table theory.

机构信息

Institute of Genetics and Biometry, Research Institute for Farm Animal Biology (FBN), Dummerstorf, Germany.

出版信息

PLoS One. 2022 Feb 24;17(2):e0262502. doi: 10.1371/journal.pone.0262502. eCollection 2022.

Abstract

The analysis of contingency tables is a powerful statistical tool used in experiments with categorical variables. This study improves parts of the theory underlying the use of contingency tables. Specifically, the linkage disequilibrium parameter as a measure of two-way interactions applied to three-way tables makes it possible to quantify Simpson's paradox by a simple formula. With tests on three-way interactions, there is only one that determines whether the partial interactions of all variables agree or whether there is at least one variable whose partial interactions disagree. To date, there has been no test available that determines whether the partial interactions of a certain variable agree or disagree, and the presented work closes this gap. This work reveals the relation of the multiplicative and the additive measure of a three-way interaction. Another contribution addresses the question of which cells in a contingency table are fixed when the first- and second-order marginal totals are given. The proposed procedure not only detects fixed zero counts but also fixed positive counts. This impacts the determination of the degrees of freedom. Furthermore, limitations of methods that simulate contingency tables with given pairwise associations are addressed.

摘要

列联表分析是一种用于分类变量实验的强大统计工具。本研究改进了列联表应用的理论基础的部分内容。具体来说,作为衡量双向相互作用的列联表中的连锁不平衡参数可以通过一个简单的公式来量化辛普森悖论。通过对三向相互作用的检验,只有一个检验可以确定所有变量的部分相互作用是否一致,或者是否至少有一个变量的部分相互作用不一致。到目前为止,还没有可用的检验来确定某个变量的部分相互作用是否一致,而本研究填补了这一空白。本研究揭示了三向相互作用的乘法和加法度量之间的关系。另一项贡献涉及了当给定一阶和二阶边缘总和时,列联表中的哪些单元格是固定的问题。所提出的程序不仅可以检测固定的零计数,还可以检测固定的正计数。这会影响自由度的确定。此外,还解决了给定成对关联模拟列联表的方法的局限性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11a/8870532/a8aff881098e/pone.0262502.g001.jpg

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