西班牙肠侵袭性大肠杆菌的发病率。一项为期14个月的前瞻性研究。

Incidence of enteroinvasive Escherichia coli in Spain. A 14-month prospective study.

作者信息

Pumarola A, Prats G, Mirelis B, Calaf A, Torruella T, Jimenez De Anta M T, Salvado M, Llorens E

出版信息

Microbiologica. 1986 Apr;9(2):215-20.

PMID:3520244

Abstract

Between February 1984 and May 1985, a prospective study was performed in patients with acute enteritis to determine the incidence of enteroinvasive Escherichia coli (ECEI) in our environment. Eight hundred and forty-three strains of E. coli were studied by agglutination with antisera for serogroups O28ac, 029, 0112, 0124, 0136, 0144, 0152 and 0164. Eleven strains were found to pertain to one or another of these serogroups: 6 to 029, 2 to 0124, 2 to 0164 and 1 to 0143. Of these, only the two corresponding to 0124 invaded HeLa cells and had a positive Sereny test. These strain were lysine decarboxylase and lactose negative and did not produce gas. In 125 strains that did not belong to any of the enteroinvasise serogroups indicated, but had been isolated from patients with febrile enteritis in which no other enteropathogen could be isolated (32 strains), or had metabolic characteristics of enteroinvasive Escherichia coli (93) strains, the Sereny test and invasion of HeLa cells were studied. In every case, both tests were negative.

摘要

1984年2月至1985年5月，对急性肠炎患者进行了一项前瞻性研究，以确定我们环境中肠侵袭性大肠杆菌（ECEI）的发病率。用针对O28ac、O29、O112、O124、O136、O144、O152和O164血清群的抗血清通过凝集试验研究了843株大肠杆菌。发现有11株属于这些血清群中的一种或另一种：6株属于O29，2株属于O124，2株属于O164，1株属于O143。其中，只有对应于O124的两株侵袭了HeLa细胞且Sereny试验呈阳性。这些菌株赖氨酸脱羧酶和乳糖阴性，不产气。在125株不属于上述任何肠侵袭性血清群，但从发热性肠炎患者中分离出来且未分离出其他肠道病原体的菌株（32株），或具有肠侵袭性大肠杆菌代谢特征的菌株（93株）中，研究了Sereny试验和HeLa细胞侵袭情况。在每种情况下，两项试验均为阴性。