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中国零售药店的抗生素管理与获取-过度使用挑战:政策综述

Antibiotic Stewardship in Retail Pharmacies and the Access-Excess Challenge in China: A Policy Review.

作者信息

Zhang Tingting, Lambert Helen, Zhao Linhai, Liu Rong, Shen Xingrong, Wang Debin, Cabral Christie

机构信息

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.

School of Health Services Management, Anhui Medical University, Hefei 230032, China.

出版信息

Antibiotics (Basel). 2022 Jan 21;11(2):141. doi: 10.3390/antibiotics11020141.

Abstract

In China, efforts to restrict excessive antibiotic consumption may prevent sufficient access to these life-saving drugs among the most deprived in society because of the weak primary health care system. This makes antibiotic stewardship in the retail pharmacy sector a particular challenge. We conducted an analysis to examinate policies on antibiotic sales in retail pharmacies in China and how tensions between 'excess' and 'access' are managed. The analysis was guided by the Walt and Gilson health policy analysis triangle to systematically analyse policies based on the content of policies, contexts, governance processes, and actors. Nine research studies and 25 documents identified from national and international sources were extracted, grouped into categories, and examined within and across records and categories. As of 2020, eight key policies have been introduced in China that focus on two areas: dispending prescribed medicines or antimicrobials with a prescription and having a licensed pharmacist present in the retail pharmacies, with approaches having changed over time. Inappropriate sales of antibiotics are still common in retail pharmacies, which can be linked to the lack of consistency and enforcement of published policies, the profit-driven nature of retail pharmacies, and the displacement of the demand for antibiotics from clinical into less regulated settings.

摘要

在中国,由于基层医疗保健系统薄弱,限制抗生素过度使用的努力可能会导致社会中最贫困人群无法充分获得这些救命药物。这使得零售药店领域的抗生素管理成为一项特殊挑战。我们进行了一项分析,以审视中国零售药店抗生素销售政策,以及如何应对“过度”与“可及性”之间的矛盾。该分析以沃尔特和吉尔森健康政策分析三角为指导,根据政策内容、背景、治理过程和行为主体对政策进行系统分析。从国内和国际来源识别出的9项研究和25份文件被提取出来,归类分组,并在记录和类别内部及之间进行审视。截至2020年,中国已出台八项关键政策,重点关注两个领域:凭处方配售处方药或抗菌药物以及零售药店配备执业药师,且这些方法随时间有所变化。零售药店中抗生素的不当销售仍然很常见,这可能与已发布政策缺乏一致性和执行力、零售药店的逐利性质以及抗生素需求从临床转向监管较松的场所有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2bc/8868274/e8f6ae77e49c/antibiotics-11-00141-g001.jpg

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