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艰难梭菌肠炎:病例报告与文献综述

Clostridioides Difficile Enteritis: Case Report and Literature Review.

作者信息

Klimko Artsiom, Tieranu Cristian George, Curte Ana-Maria, Preda Carmen Monica, Tieranu Ioana, Olteanu Andrei Ovidiu, Ionescu Elena Mirela

机构信息

Division of Physiology and Neuroscience, "Carol Davila" University of Medicine and Pharmacy, 050747 Bucharest, Romania.

Department of Gastroenterology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

出版信息

Antibiotics (Basel). 2022 Feb 6;11(2):206. doi: 10.3390/antibiotics11020206.

Abstract

is a well-known pathogen causing diarrhea of various degrees of severity through associated infectious colitis. However, there have been reports of infectious enteritis mainly in patients with ileostomy, causing dehydration through high-output volume; Case presentation: We report the case of a 46-year-old male patient, malnourished, who presented with high-output ileostomy following a recent hospitalization where he had suffered an ileo-colic resection with ileal and transverse colon double ostomy, for stricturing Crohn's disease. toxin A was identified in the ileal output confirming the diagnosis of acute enteritis. Treatment with oral Vancomycin was initiated with rapid reduction of the ileostomy output volume; Conclusion: We report a case of enteral infection as a cause for high-output ileostomy, successfully treated with oral Vancomycin. We also review the existing literature data regarding this specific localized infection.

摘要

是一种通过相关感染性结肠炎导致不同程度严重腹泻的知名病原体。然而,主要有关于回肠造口术患者感染性肠炎的报道,通过高排出量导致脱水;病例报告:我们报告一例46岁男性患者,营养不良,近期住院后出现高排出量回肠造口术,他因狭窄性克罗恩病接受了回肠 - 结肠切除术及回肠和横结肠双造口术。在回肠排出物中鉴定出毒素A,证实了急性肠炎的诊断。开始口服万古霉素治疗,回肠造口术排出量迅速减少;结论:我们报告一例肠内感染导致高排出量回肠造口术的病例,口服万古霉素成功治愈。我们还回顾了关于这种特定局部感染的现有文献数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b68d/8868300/4a8a31c9d870/antibiotics-11-00206-g001.jpg

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