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阿米巴病的免疫诊断结果。对流免疫电泳与其他三种免疫检测方法相比的价值(作者译)

[Immunodiagnostic results of amoebiasis. The value of counter immunoelectrophoresis in comparison to three other immunotests (author's transl)].

作者信息

Mannweiler E, Lederer I

出版信息

Zentralbl Bakteriol Orig A. 1978 Apr;240(3):403-8.

PMID:352040
Abstract

63 cases of extraintestinal amoebiasis, 17 cases of intestinal amoebiasis, and 25 selected control persons were examined for serum antibodies to antigen from E. histolytica using the counter-immunoelectrophoresis, the complement fixation test, the indirect haemagglutination test and the latex agglutination test. In addition counter-immunoelectrophoresis was applied to 41 sera from patients with extraintestinal amoebiasis whose other serological results were included in a previous study. Even with the employment of our immunological methods, the test results can be used for diagnostic purposes only when they are in accordance with the clinical picture and the exposure. Complete failures of the immuno-diagnostic tests did not occur in our study. On the other hand, there are persons with no symptoms of amoebiasis who have antibodies in two tests, among them sometimes the counter-immunoelectrophoresis, with levels corresponding to those of intestinal or extra-intestinal amoebiasis.

摘要

对63例肠外阿米巴病患者、17例肠阿米巴病患者以及25名选定的对照人员,采用对流免疫电泳、补体结合试验、间接血凝试验和乳胶凝集试验检测其血清中抗溶组织内阿米巴抗原的抗体。此外,对41例肠外阿米巴病患者的血清进行了对流免疫电泳检测,这些患者的其他血清学检测结果已纳入先前的一项研究。即使采用我们的免疫学方法,只有当检测结果与临床表现和接触史相符时,才能用于诊断目的。在我们的研究中,免疫诊断试验并未完全失败。另一方面,有无阿米巴病症状的人在两项检测中出现抗体,其中有时在对流免疫电泳中出现抗体,其水平与肠阿米巴病或肠外阿米巴病患者的水平相当。

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