Miyata Hidemasa, Tani Ryouji, Toratani Shigeaki, Okamoto Tetsuji
Department of Molecular Oral Medicine and Maxillofacial Surgery, Graduate School of Biomedical & Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8553, Japan.
Oral and Maxillofacial Surgery, Hiroshima University Hospital, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8553, Japan.
Brain Sci. 2022 Feb 21;12(2):296. doi: 10.3390/brainsci12020296.
Tongue pressure measurement (TPM) is an indicator of oral function. However, the association between tongue pressure and cerebral activation remains unclear. We used near-infrared spectroscopy (NIRS) to examine the correlation between cerebral cortex activation and tongue pressure stimulation against the anterior palatal mucosa. We measured voluntary maximum tongue pressure (MTP) using a TPM device; a pressure value of approximately 60% of the MTP was used for the experimental tongue pressure (MTP). We examined the effect of oral functional tongue pressure stimulation against the anterior palatal mucosa on cerebral activation using NIRS in 13 adults. Tongue pressure stimulation caused significant changes in cerebral blood flow in some areas compared with controls ( < 0.05). We performed a correlation analysis ( < 0.05) between MTP and changes in oxygenated hemoglobin in all 47 NIRS channels. MTP triggered activation of the right somatosensory motor area and right dorsolateral prefrontal cortex and deactivation of the anterior prefrontal cortex (APFC). TPM balloon-probe insertion in the oral cavity activated the bilateral somatosensory motor area and deactivated the wide area of the APFC. Moreover, MTP via the TPM balloon probe activated the bilateral somatosensory and motor cortex areas. Tongue pressure stimulation changes cerebral blood flow, and NIRS is useful in investigating the relationship between oral stimulation and brain function.
舌压测量（TPM）是口腔功能的一个指标。然而，舌压与大脑激活之间的关联仍不明确。我们使用近红外光谱（NIRS）来研究大脑皮层激活与针对腭前黏膜的舌压刺激之间的相关性。我们使用TPM设备测量自主最大舌压（MTP）；实验性舌压（MTP）采用约为MTP 60%的压力值。我们使用NIRS研究了13名成年人中针对腭前黏膜的口腔功能性舌压刺激对大脑激活的影响。与对照组相比，舌压刺激在某些区域引起了脑血流量的显著变化（<0.05）。我们对所有47个NIRS通道中的MTP与氧合血红蛋白变化进行了相关性分析（<0.05）。MTP触发了右侧体感运动区和右侧背外侧前额叶皮层的激活以及前额叶前部皮层（APFC）的失活。将TPM气囊探头插入口腔激活了双侧体感运动区并使APFC的广泛区域失活。此外，通过TPM气囊探头施加的MTP激活了双侧体感和运动皮层区域。舌压刺激会改变脑血流量，并且NIRS有助于研究口腔刺激与脑功能之间的关系。
