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[精神分裂症中抗胸腺细胞抗体的定量评估]

[Quantitative assessment of antithymocyte antibodies in schizophrenia].

作者信息

Kushner S G, Maznina T P, Bunimovich L A

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(5):697-700.

PMID:352070
Abstract

The use of the method of fluorescent antibodies and cytotoxic tests showed that the blood serum of schizophrenic patients and normals possess an antithymocytic activity. However, the level of this activity in patients exceeds the corresponding indices in normals (p less than 0.02). The use of indirect immunofluorescent methods permitted to demonstrate that the antithymic antibody titres in schizophrenic patients is much higher than in normals. The amount of the cytotoxic index is in direct correlation with the level of antithymic antibodies determined by the fluorescent antibody method.

摘要

荧光抗体法和细胞毒性试验的应用表明,精神分裂症患者和正常人的血清均具有抗胸腺细胞活性。然而,患者体内这种活性水平超过了正常人的相应指标(p小于0.02)。间接免疫荧光法的应用证实,精神分裂症患者的抗胸腺抗体滴度远高于正常人。细胞毒性指数的数值与通过荧光抗体法测定的抗胸腺抗体水平直接相关。

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