Kushner S G, Maznina T P
Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(7):1071-4.
The study was conducted by the immune absorption method. The serum activity before and after absorption was studied with the cytotoxic test and the fluorescent antibody method. The studies demonstrated that antibodies, detected in the blood serum of patients and normals differ not only qualitatively but also quantitatively. It was established as well that antibodies detected in normals may be completely absorbed by the brain and thymus of mice or by similar human tissues. In absorption of antibodies in patients by tissues of mice, the activity of the sera entirely disappears. On the contrary, the brain tissue and human thymocytes only insignificantly decrease the serum titres in patients.
该研究采用免疫吸附法进行。通过细胞毒性试验和荧光抗体法研究了吸附前后的血清活性。研究表明,患者和正常人血清中检测到的抗体不仅在质量上不同,而且在数量上也不同。还确定正常人血清中检测到的抗体可被小鼠的脑和胸腺或类似的人体组织完全吸附。在小鼠组织吸附患者血清中的抗体时,血清活性完全消失。相反,脑组织和人胸腺细胞只会使患者血清滴度略有下降。