眼眶癌肉瘤：两例报告并文献复习
Carcinosarcoma of the orbit: report of two cases and review of the literature.
作者信息
Prakalapakorn Sasapin G, Bernardino C Robert, Auclair Paul L, Grossniklaus Hans E
机构信息
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
出版信息
Ophthalmology. 2008 Nov;115(11):2065-70. doi: 10.1016/j.ophtha.2008.04.037. Epub 2008 Jun 17.
OBJECTIVE
To report the clinicopathologic features of 2 patients with carcinosarcoma of the orbit.
DESIGN
Case reports.
PARTICIPANTS
Two patients with orbital carcinosarcoma were identified.
METHODS
Retrospective chart review with clinicopathologic correlation and literature review.
MAIN OUTCOME MEASURES
Clinical examination, imaging studies, and histopathologic findings.
RESULTS
Two patients, a 56-year-old woman and a 91-year-old woman, with orbital carcinosarcoma were identified. Both tumors contained sarcomatous and carcinomatous components and invaded periorbital structures.
CONCLUSIONS
Carcinosarcoma may arise in the orbit or extend into the orbit from the paranasal sinuses. This malignant neoplasm should be aggressively treated with a combination of surgical resection, chemotherapy, and radiation therapy.
目的
报告2例眼眶癌肉瘤的临床病理特征。
设计
病例报告。
研究对象
确定了2例眼眶癌肉瘤患者。
方法
回顾性病历审查并结合临床病理分析及文献复习。
主要观察指标
临床检查、影像学检查及组织病理学检查结果。
结果
确定了2例眼眶癌肉瘤患者，分别为一名56岁女性和一名91岁女性。两个肿瘤均包含肉瘤和癌成分，并侵犯眶周结构。
结论
癌肉瘤可起源于眼眶或从鼻窦延伸至眼眶。这种恶性肿瘤应采用手术切除、化疗和放疗相结合的积极治疗方法。
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