Department of Botany, School of Chemical and Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi 110062, India.
School of Chemical Engineering, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, Korea.
Molecules. 2022 Feb 19;27(4):1407. doi: 10.3390/molecules27041407.
Traditionally, medicinal plants have long been used as a natural therapy. Plant-derived extracts or phytochemicals have been exploited as food additives and for curing many health-related ailments. The secondary metabolites produced by many plants have become an integral part of human health and have strengthened the value of plant extracts as herbal medicines. To fulfil the demand of health care systems, food and pharmaceutical industries, interest in the cultivation of precious medicinal plants to harvest bio-active compounds has increased considerably worldwide. To achieve maximum biomass and yield, growers generally apply chemical fertilizers which have detrimental impacts on the growth, development and phytoconstituents of such therapeutically important plants. Application of beneficial rhizosphere microbiota is an alternative strategy to enhance the production of valuable medicinal plants under both conventional and stressed conditions due to its low cost, environmentally friendly behaviour and non-destructive impact on fertility of soil, plants and human health. The microbiological approach improves plant growth by various direct and indirect mechanisms involving the abatement of various abiotic stresses. Given the negative impacts of fertilizers and multiple benefits of microbiological resources, the role of plant growth promoting rhizobacteria (PGPR) in the production of biomass and their impact on the quality of bio-active compounds (phytochemicals) and mitigation of abiotic stress to herbal plants have been described in this review. The PGPR based enhancement in the herbal products has potential for use as a low cost phytomedicine which can be used to improve health care systems.
传统上，药用植物一直被用作天然疗法。植物提取物或植物化学物质已被用作食品添加剂，并用于治疗许多与健康相关的疾病。许多植物产生的次生代谢物已成为人类健康的不可或缺的一部分，并增强了植物提取物作为草药的价值。为了满足医疗保健系统、食品和制药行业的需求，全球对种植珍贵药用植物以收获生物活性化合物的兴趣大大增加。为了获得最大的生物量和产量，种植者通常会使用化肥，这会对这些具有治疗重要性的植物的生长、发育和植物化学成分产生不利影响。由于其成本低、对环境友好且对土壤、植物和人类健康的肥力没有破坏性影响，有益根际微生物群的应用是一种在常规和胁迫条件下提高有价值药用植物产量的替代策略。微生物方法通过各种直接和间接的机制来促进植物生长，包括减轻各种非生物胁迫。鉴于化肥的负面影响和微生物资源的多种益处，本综述描述了植物生长促进根际细菌（PGPR）在生物量生产及其对生物活性化合物（植物化学物质）质量的影响以及减轻草药植物非生物胁迫方面的作用。基于 PGPR 的草药产品增强具有作为低成本植物药的潜力，可用于改善医疗保健系统。
