Dom R, De Mesmaecker L, van den Broucke M, van Hest T, Baro F
Acta Psychiatr Scand. 1978 Apr;57(4):299-304. doi: 10.1111/j.1600-0447.1978.tb06898.x.
The clinical effect of clopenthixol decanoate has been assessed in a 5-month controlled including 21 hospitalized chronic schizophrenic patients. The ratings were done with BPRS, NOSIE 30, the two psychological tests of WAIS and Grübaum, and the rating scale of Simpson & Angus to assess extrapyramidal side effects. Clopenthixol decanoate was found an effective and long-acting antipsychotic compound with few autonomic and neurological side effects. Compared with previous maintenance treatment it also showed a positive influence on depression and facilitation of the social adaptation of the patients.
已对21名住院慢性精神分裂症患者进行了为期5个月的对照试验，以评估癸酸氯哌噻吨的临床疗效。采用简明精神病评定量表（BPRS）、护士用住院病人观察量表（NOSIE 30）、韦氏成人智力量表（WAIS）和格鲁鲍姆两项心理测试以及辛普森和安格斯评定量表来评估锥体外系副作用，对患者进行评分。结果发现癸酸氯哌噻吨是一种有效且长效的抗精神病化合物，自主神经和神经方面的副作用较少。与先前的维持治疗相比，它对抑郁症也有积极影响，并有助于患者的社会适应。
