Institute for Disaster Management and Reconstruction of Sichuan University and Hong Kong Polytechnic University & West China School of Public Health, Sichuan University, Chengdu, China
Department of General Surgery, The General Hospital of Western Theater Command, Chengdu, China.
BMJ Open. 2022 Feb 24;12(2):e051694. doi: 10.1136/bmjopen-2021-051694.
To systematically assess the prevalence and risk factors for senile pruritus (SP) in the elderly (≥60 years of age).
A meta-analysis was used to pool the prevalence and risk factors for SP estimated from individual studies. Four subgroup analyses were conducted to explore the prevalence for SP in different age, sex, research sites and region.
SETTING, PARTICIPANTS AND MEASURES: SP reduces quality of life in the elderly, yet the worldwide prevalence is unclear. Moreover, the risk factors for SP are controversial. Data from cross-sectional studies, case-control studies, longitudinal studies and cohort studies that reported the prevalence or the risk factors for SP were collected by searching nine electronic databases up to October 2020, including Web of Science, PubMed, Embase, Cochrane Library, CINAHL, CBM, CNKI, Wanfang and VIP. Two reviewers independently screened studies according to the inclusion and exclusion criteria, extracted data and assessed methodological quality. Data analysis was performed using Stata V.15.1 software.
Seventeen studies involving 28 666 participants were included. The overall pooled prevalence of SP was 21.04% (95% CI 11.37% to 32.72%). In addition, the results showed that smoking, excessive drinking and monophagism were possible risk factors for SP, with pooled ORs of 1.26 (95% CI 1.14 to 1.40), 25.03 (95% CI 18.28 to 34.25) and 1.22 (95% CI 1.12 to 1.33), respectively.
The overall prevalence of SP was high. Smoking, excessive drinking and monophagism were possible risk factors for SP.
CRD42019143295.
系统评估老年人（≥60 岁）瘙痒症的患病率和危险因素。
采用荟萃分析方法对来自个体研究的瘙痒症患病率和危险因素进行汇总。进行了 4 项亚组分析，以探讨不同年龄、性别、研究地点和地区瘙痒症的患病率。
设置、参与者和措施：瘙痒症降低老年人的生活质量，但全球患病率尚不清楚。此外，瘙痒症的危险因素存在争议。通过检索 9 个电子数据库（包括 Web of Science、PubMed、Embase、Cochrane Library、CINAHL、CBM、CNKI、万方和 VIP），截至 2020 年 10 月，收集了报告瘙痒症患病率或危险因素的横断面研究、病例对照研究、纵向研究和队列研究的数据。两名审查员根据纳入和排除标准独立筛选研究，提取数据并评估方法学质量。使用 Stata V.15.1 软件进行数据分析。
纳入了 17 项涉及 28666 名参与者的研究。瘙痒症的总患病率为 21.04%（95%CI 11.37%至 32.72%）。此外，结果表明，吸烟、酗酒和偏食可能是瘙痒症的危险因素，其汇总 OR 分别为 1.26（95%CI 1.14 至 1.40）、25.03（95%CI 18.28 至 34.25）和 1.22（95%CI 1.12 至 1.33）。
瘙痒症的总体患病率较高。吸烟、酗酒和偏食可能是瘙痒症的危险因素。
PROSPERO 注册号：CRD42019143295。
