Pur Daiana Roxana, Catherine Danielle Bursztyn Lulu Liane, Iordanous Yiannis
Schulich School of Medicine and Dentistry, Western University, London, ON, N6A 3K7, Canada.
Department of Ophthalmology, Schulich School of Medicine and Dentistry, Western University, London, ON, N6A 3K7, Canada.
Am J Ophthalmol Case Rep. 2022 Jun;26:101445. doi: 10.1016/j.ajoc.2022.101445. Epub 2022 Feb 18.
To report a case of a branch retinal vein occlusion (BRVO) following mRNA COVID-19 vaccination.
A 34-year-old healthy male presented with blurriness in the inferior visual field, intermittent photopsia, multiple retinal hemorrhages, dilated and tortuous retinal vessels, and cotton wools spots in the right eye. The clinical examination and ancillary tests confirmed the diagnosis of a right eye BRVO. The visual symptoms started 2 days following first dose COVID-19 vaccination with the BNT162b2 (Pfizer-BioNTech) mRNA vaccine.
This is a rare case of BRVO in an otherwise healthy young man, presenting after vaccination for COVID-19 in the absence of other coagulable risk factors. As the literature on venous thrombosis after COVID-19 vaccinations remains sparse, it is critical to raise awareness that BRVO could be a vaccine-related thrombotic adverse event. We highlight that as more of the population is vaccinated, an increased incidence of BRVO may confirm the link to COVID-19 vaccination.
报告1例新型冠状病毒肺炎（COVID-19）mRNA疫苗接种后发生视网膜分支静脉阻塞（BRVO）的病例。
一名34岁健康男性出现右下视野模糊、间歇性闪光感、多处视网膜出血、视网膜血管扩张迂曲以及右眼棉絮斑。临床检查和辅助检查确诊为右眼BRVO。视觉症状在首次接种BNT162b2（辉瑞 - 生物科技公司）mRNA COVID-19疫苗2天后出现。
这是1例在无其他可导致凝血风险因素的健康年轻男性中发生的罕见BRVO病例，在接种COVID-19疫苗后出现。由于关于COVID-19疫苗接种后静脉血栓形成的文献仍然稀少，提高对BRVO可能是疫苗相关血栓性不良事件的认识至关重要。我们强调，随着更多人群接种疫苗，BRVO发病率的增加可能证实其与COVID-19疫苗接种的关联。
