Zipes D P, Troup P J
Am J Cardiol. 1978 May 22;41(6):1005-24. doi: 10.1016/0002-9149(78)90853-6.
The present status, clinical experience, side effects, clinical pharmacology and electrophysiologic actions of seven new antiarrhythmic agents are reviewed. The drugs selected for comment are amiodarone, aprindine, disopyramide, ethmozin, mexiletine, tocainide and verapamil. Each drug has been shown to have clinical efficacy in suppressing cardiac arrhythmias.
本文综述了七种新型抗心律失常药物的现状、临床经验、副作用、临床药理学及电生理作用。文中所评论的药物有胺碘酮、茚满丙二胺、双异丙吡胺、乙吗噻嗪、美西律、妥卡尼及维拉帕米。已证实每种药物在抑制心律失常方面均有临床疗效。