Kumar S Pravin, Asokan Yuvasri, Balamurugan Keerthana, Harsha B
Center for Healthcare Technologies, Department of Biomedical Engineering, Sri Sivasubramaniya Nadar college of Engineering, Chennai, India.
J Med Eng Technol. 2022 May;46(4):318-334. doi: 10.1080/03091902.2022.2041750. Epub 2022 Feb 25.
A wound is a trauma caused by some adverse external or blunt forces that can damage the body tissues. Wound healing is a complex process that occurs post-injury which involves the revamping of the structure and function of damaged tissues. Scaffolds are engineered tissue structures manufactured using different materials and methods for facilitating the wound healing process. For external wounds, the antimicrobial property and ability to absorb moisture play an important role in the material selection of the scaffold. Among different methods that exist for designing scaffolds, three-dimensional printing has emerged as a promising technique wherein customised scaffolds can be designed. However, the literature on three-dimensional printed dressings is very much limited compared to conventional ones. Therefore, this review specifically focuses on the methods used to design the scaffolds with special emphasis on different three-dimensional printing techniques. It covers the process of external wound healing, different materials used in the fabrication of scaffolds, and their advantages and drawbacks.
伤口是由一些不利的外部或钝性力量造成的创伤，会损害身体组织。伤口愈合是受伤后发生的一个复杂过程，涉及受损组织结构和功能的修复。支架是使用不同材料和方法制造的工程化组织结构，用于促进伤口愈合过程。对于外部伤口，抗菌性能和吸湿能力在支架材料选择中起着重要作用。在现有的设计支架的不同方法中，三维打印已成为一种很有前景的技术，可设计定制化支架。然而，与传统敷料相比，关于三维打印敷料的文献非常有限。因此，本综述特别关注用于设计支架的方法，尤其着重于不同的三维打印技术。它涵盖了外部伤口愈合的过程、支架制造中使用的不同材料及其优缺点。
