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乳酸菌合成的胞外多糖:生物合成途径、结构-功能关系、结构修饰及应用

Exopolysaccharides synthesized by lactic acid bacteria: biosynthesis pathway, structure-function relationship, structural modification and applicability.

作者信息

Wu Jinsong, Han Xiangpeng, Ye Meizhi, Li Yao, Wang Xi, Zhong Qingping

机构信息

Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou, China.

Department of Science, Henan University of Animal Husbandry and Economy, Henan, Zhengzhou, China.

出版信息

Crit Rev Food Sci Nutr. 2023;63(24):7043-7064. doi: 10.1080/10408398.2022.2043822. Epub 2022 Feb 25.

Abstract

Probiotics and their fermentation products are increasingly been focused on due to their health-boosting effects. Exopolysaccharides (EPS) synthetized by lactic acid bacteria (LAB) are widely applied as texture modifiers in dairy, meat and bakery products owning to their improved properties. Moreover, LAB-derived EPS have been confirmed to possess diverse physiological bioactivities including antioxidant, anti-biofilm, antiviral, immune-regulatory or antitumor. However, the low production and high acquisition cost hinder their development. Even though LAB-derived EPS have been extensively studied for their production-improving, there are only few reports on the systematic elucidation and summary of the relationship among biosynthesis pathway, strain selection, production parameter, structure-function relationship. Therefore, a detailed summary on biosynthesis pathway, production parameter and structure-function relationship of LAB-derived EPS is provided in this review, the structural modifications together with the current and potential applications are also discussed in this paper.

摘要

由于益生菌及其发酵产物具有促进健康的作用,它们越来越受到关注。乳酸菌合成的胞外多糖因其改良特性而被广泛用作乳制品、肉类和烘焙食品的质地改良剂。此外,已证实乳酸菌来源的胞外多糖具有多种生理生物活性,包括抗氧化、抗生物膜、抗病毒、免疫调节或抗肿瘤。然而,产量低和获取成本高阻碍了它们的发展。尽管对乳酸菌来源的胞外多糖提高产量的研究已经很广泛,但关于生物合成途径、菌株选择、生产参数、结构-功能关系之间关系的系统阐释和总结的报道却很少。因此,本综述对乳酸菌来源的胞外多糖的生物合成途径、生产参数和结构-功能关系进行了详细总结,本文还讨论了其结构修饰以及当前和潜在的应用。

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