Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA.
Hum Vaccin Immunother. 2021 Dec 2;17(12):5407-5412. doi: 10.1080/21645515.2021.2005436.
Gay, bisexual, and other men who have sex with men (MSM) and transgender women are disproportionately affected by human papillomavirus (HPV). HPV vaccination is routinely recommended for U.S. adolescents at age 11-12 years, with catch-up vaccination through age 26 years. We assessed HPV vaccination coverage and associated factors among young MSM and transgender women. The Vaccine Impact in Men study enrolled MSM aged 18-26 years from clinics in Seattle, Chicago, and Los Angeles, during February 2016-September 2018. Participants self-reported socio-demographic information and HPV vaccination status. Among 1416 participants, 673 (47.5%) reported ≥1 HPV vaccine dose. Among vaccinated participants, median age at first dose was 19 years and median age at first sex was 17 years; 493 (73.3%) reported that their age at first dose was older than their age at first sex. There were significant differences in HPV vaccination coverage by city (range 33%-62%), age, race/ethnicity, and gender identity. Coverage was highest in Seattle, where younger age was the only factor associated with vaccination. Differences in coverage by city may be due to variation in vaccination practices or enrollment at study sites. Increasing both routine and catch-up vaccination will improve coverage among MSM and transgender women.
男同性恋者、双性恋者和其他与男性发生性行为的男性（MSM）以及跨性别女性受到人乳头瘤病毒（HPV）的影响不成比例。美国常规建议 11-12 岁的青少年接种 HPV 疫苗，并在 26 岁之前补种。我们评估了年轻 MSM 和跨性别女性的 HPV 疫苗接种率和相关因素。疫苗影响男性研究于 2016 年 2 月至 2018 年 9 月期间在西雅图、芝加哥和洛杉矶的诊所招募了 18-26 岁的 MSM。参与者自我报告社会人口统计学信息和 HPV 疫苗接种状况。在 1416 名参与者中，有 673 名（47.5%）报告至少接种了 1 剂 HPV 疫苗。在接种疫苗的参与者中，首剂年龄中位数为 19 岁，首次性行为年龄中位数为 17 岁；493 名（73.3%）报告他们的首剂年龄大于首次性行为年龄。HPV 疫苗接种率因城市（范围为 33%-62%）、年龄、种族/族裔和性别认同而存在显著差异。在西雅图，接种率最高，而年龄较小是唯一与接种相关的因素。城市间覆盖率的差异可能是由于接种实践或研究地点的登记差异造成的。增加常规和补种疫苗接种将提高 MSM 和跨性别女性的疫苗接种率。
