[氨曲南对1990株近期从坎帕尼亚医院分离出的革兰氏阴性菌的体外活性评估]
[Evaluation of the in vitro activity of aztreonam on 1990 gram-negative bacterial strains recently isolated in Campania hospitals].
作者信息
Covelli I, Bolletti-Censi M, Fortunato A, Guarino A, Spagnoletti G, Amato G, Nani E, Anzivino D, Lavitola A, Gulletta E
出版信息
Boll Ist Sieroter Milan. 1986;65(1):22-31.
The in vitro activity of aztreonam, leader of a new class of antibiotics, the monobactams, has been investigated. The effectiveness of the new molecule on 1990 strains of Gram-negative clinical isolates has been compared to that of some other drugs widely utilized for the treatment of nosocomial infections. Aztreonam has shown the highest activity against all the tested strains, with a geometrical mean of MICs (MG) of 0.37 and a MIC 90 of 8 micrograms/ml.
氨曲南是新型抗生素单环β-内酰胺类的代表药物，其体外活性已得到研究。已将这种新分子对1990株革兰氏阴性临床分离株的有效性与其他一些广泛用于治疗医院感染的药物进行了比较。氨曲南对所有测试菌株均显示出最高活性，MIC几何平均值（MG）为0.37，MIC90为8微克/毫升。
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