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关节突囊肿治疗结局与不良事件的系统评价和荟萃分析

A Systematic Review and Meta-Analysis of Outcomes and Adverse Events for Juxtafacet Cysts Treatment.

作者信息

Giordan Enrico, Gallinaro Paolo, Stafa Altin, Canova Giuseppe, Zanata Roberto, Marton Elisabetta, Verme Jacopo Del

机构信息

Department of Neurosurgery, Aulss 2 Marca Trevigiana, Treviso, Veneto, Italy

Department of Neurosurgery, Aulss 2 Marca Trevigiana, Treviso, Veneto, Italy.

出版信息

Int J Spine Surg. 2022 Feb;16(1):124-138. doi: 10.14444/8181. Epub 2022 Feb 25.

Abstract

BACKGROUND

Different procedures have been used for the treatment of lumbar juxtafacet cysts (JFCs). Recently, full-endoscopic cyst excision has been suggested as a reasonable alternative. We performed a meta-analysis to assess the overall rates of favorable outcomes and adverse events for each available treatment and determine the outcome and complication rates concerning spine stability.

METHODS

Multiple databases were searched for English-language studies involving adult patients with lumbar JFCs who had been followed for more than 6 months. Outcomes included the proportion of patients with a satisfactory outcome. Adverse events included recurrence and revision rates as well as intraoperative complications. We further stratified the analysis based on the spine's condition (degenerative listhesis vs without degenerative listhesis).

RESULTS

A total of 43 studies, including 2226 patients, were identified. Over 80% of patients experienced satisfactory improvement after surgical excision but only 66.2% after percutaneous cyst rupture and aspiration. Overall, recurrence and revision rates were almost double in patients with preoperative degenerative listhesis at the cyst level, especially in the minimally invasive group (2.1% vs 31.3% and 6.8% vs 13.1%, respectively). The rate of full-endoscopic satisfactory outcomes was approximately 90%, with low rates of adverse events (<2%).

CONCLUSION

We analyzed the outcome and adverse event rates for each kind of available treatment for JFC. Full endoscopy has outcomes and rates of adverse events that overlap with open and minimally invasive approaches.

LEVEL OF EVIDENCE

2A.

摘要

背景

已采用不同的手术方法治疗腰椎关节突囊肿(JFC)。最近,全内镜下囊肿切除术被认为是一种合理的替代方法。我们进行了一项荟萃分析,以评估每种可用治疗方法的总体良好结局率和不良事件发生率,并确定与脊柱稳定性相关的结局和并发症发生率。

方法

检索多个数据库,查找涉及随访时间超过6个月的成年腰椎JFC患者的英文研究。结局包括结局满意的患者比例。不良事件包括复发率、翻修率以及术中并发症。我们根据脊柱状况(退行性滑脱与无退行性滑脱)进一步分层分析。

结果

共纳入43项研究,包括2226例患者。超过80%的患者在手术切除后病情得到满意改善,但经皮囊肿破裂抽吸术后只有66.2%的患者病情得到满意改善。总体而言,囊肿水平存在术前退行性滑脱的患者的复发率和翻修率几乎翻倍,尤其是在微创组(分别为2.1%对31.3%和6.8%对13.1%)。全内镜下满意结局的发生率约为90%,不良事件发生率较低(<2%)。

结论

我们分析了JFC每种可用治疗方法的结局和不良事件发生率。全内镜手术的结局和不良事件发生率与开放手术和微创手术方法有重叠。

证据级别

2A。

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