Kammer Pedro Vitali, Moro Juliana Silva, Soares Josiane Pezzini, Massignan Carla, Phadraig Caoimhin Mac Giolla, Bolan Michele
Department of Dentistry, Federal University of Santa Catarina - Florianópolis, Santa Catarina, Brazil.
Department of Dentistry, University of Brasilia - Brasilia, Distrito Federal, Brazil.
J Oral Rehabil. 2022 Jun;49(6):671-685. doi: 10.1111/joor.13315. Epub 2022 Mar 21.
To conduct a systematic review and meta-analysis on the prevalence of tooth grinding and/or clenching (TGC) in children and adolescents with a neurodevelopmental disorder or other developmental condition.
A search was performed in seven databases, two sources of grey literature and reference lists of included studies. Risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data. We used random-effects models with Freeman-Tukey double arcsine transformation for the meta-analyses.
After selection, 77 of the 2240 studies met inclusion criteria and were categorised by disability and type of TGC (reported, clinically observed and definitive). The pooled prevalence of reported TGC in individuals with attention-deficit hyperactivity disorder was 57.6% (95% CI [confidence interval]: 49.5-65.6), 50.4% (95% CI: 35.5-65.4) in individuals with autism spectrum disorder, 67% (95% CI: 59.2-74.8) in cerebral palsy and 68.2% (95% CI: 59.8-76.6) in Down syndrome. Pooled prevalence of clinically observed TGC was 57.5% (95% CI: 31.6-83.4) in autism spectrum disorder and 71.9% (95% CI: 52.4-91.4) in cerebral palsy. Individuals with attention-deficit hyperactivity disorder presented 39.8% (95% CI: 24-55.6) of definitive TGC.
Prevalence of reported, clinically observed, and definitive TGC varies according to disabilities, although due to high heterogeneity the result should be interpreted with caution. Variations exist mainly due to sampling bias and the use of non-validated methods to assess TGC. CRD42020212640.
对患有神经发育障碍或其他发育状况的儿童和青少年中磨牙和/或紧咬牙（TGC）的患病率进行系统评价和荟萃分析。
在七个数据库、两个灰色文献来源以及纳入研究的参考文献列表中进行检索。使用乔安娜·布里格斯研究所报告患病率数据研究的批判性评价清单评估偏倚风险。我们在荟萃分析中使用了带有弗里曼-图基双反正弦变换的随机效应模型。
经过筛选，2240项研究中的77项符合纳入标准，并根据残疾情况和TGC类型（报告的、临床观察到的和确诊的）进行分类。注意缺陷多动障碍患者报告的TGC合并患病率为57.6%（95%置信区间[CI]：49.5 - 65.6），自闭症谱系障碍患者为50.4%（95%CI：35.5 - 65.4），脑瘫患者为67%（95%CI：59.2 - 74.8），唐氏综合征患者为68.2%（95%CI：59.8 - 76.6）。自闭症谱系障碍患者临床观察到的TGC合并患病率为57.5%（95%CI：31.6 - 83.4），脑瘫患者为71.9%（95%CI：52.4 - 91.4）。注意缺陷多动障碍患者确诊的TGC为39.8%（95%CI：24 - 55.6）。
报告的、临床观察到的和确诊的TGC患病率因残疾情况而异，尽管由于高度异质性，结果应谨慎解释。差异主要源于抽样偏倚以及使用未经验证的方法评估TGC。CRD42020212640。
