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持续性产后抑郁症对儿童期心理问题的长期影响。

Long-term effect of persistent postpartum depression on children's psychological problems in childhood.

机构信息

Research Center for Child Mental Development, Hamamatsu University School of Medicine, Japan; United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Japan.

Research Center for Child Mental Development, Hamamatsu University School of Medicine, Japan; United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Japan; Department of Child and Adolescent Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.

出版信息

J Affect Disord. 2022 May 15;305:71-76. doi: 10.1016/j.jad.2022.02.061. Epub 2022 Feb 24.

Abstract

BACKGROUND

Maternal postpartum depression (PPD) is a well-established risk factor for psychological problems in children; however, little is known about the sustained impact of persistent PPD patterns and severity on these problems in children.

METHODS

Data were obtained from mothers (N = 714) and children (N = 768) from the Hamamatsu Birth Cohort for Mothers and Children. Maternal depression was measured using the Edinburgh Postpartum Depression Scale at 2, 4, 10 weeks and 10 months postpartum. Children's internalizing and externalizing problems were assessed using the Strengths and Difficulties Questionnaire at 6 years and 8-9 years old. Mothers were divided into 4 groups based on the trajectory of their PPD persistence: "No PPD," "Transient PPD," "Worsening PPD" and "Persistent PPD." Linear regression analysis was used to examine the association of PPD persistence and severity with children's internalizing and externalizing problems.

RESULTS

"Persistent PPD" was significantly associated with children's internalizing problems at 6 years old (Coefficient [95%CI] = 2.74 [1.30-4.19], P < .001), but no association was found at 8-9 years old. No associations were found between PPD severity and children's internalizing and externalizing problems in either age category.

LIMITATIONS

"Persistent PPD" and "Worsening PPD" groups had a relatively small sample size. The mothers' depression statuses were not ascertained simultaneously with the children's behavioral assessments. There was no information regarding the mothers' treatment for PPD.

CONCLUSION

PPD persistence negatively affected children's internalizing problems but was not long-lasting. Future studies are needed to identify protective factors against PPD persistence in children's psychological problems.

摘要

背景

产后抑郁症(PPD)是儿童心理问题的一个既定风险因素;然而,对于持续性 PPD 模式和严重程度对儿童这些问题的持续影响知之甚少。

方法

数据来自滨松母婴队列研究的母亲(N=714)和儿童(N=768)。母亲的抑郁程度在产后 2、4、10 周和 10 个月时使用爱丁堡产后抑郁量表进行测量。儿童的内化和外化问题在 6 岁和 8-9 岁时使用长处和困难问卷进行评估。根据 PPD 持续存在的轨迹,母亲被分为 4 组:“无 PPD”、“一过性 PPD”、“PPD 恶化”和“持续性 PPD”。线性回归分析用于检验 PPD 持续存在和严重程度与儿童内化和外化问题的关系。

结果

“持续性 PPD”与儿童 6 岁时的内化问题显著相关(系数 [95%CI] = 2.74 [1.30-4.19],P <.001),但在 8-9 岁时没有关联。在任何年龄段,PPD 严重程度与儿童的内化和外化问题均无关联。

局限性

“持续性 PPD”和“恶化性 PPD”组的样本量相对较小。母亲的抑郁状况与儿童的行为评估不是同时确定的。没有关于母亲 PPD 治疗的信息。

结论

PPD 持续存在对儿童的内化问题产生负面影响,但不具有持久性。未来的研究需要确定针对儿童心理问题的 PPD 持续性的保护因素。

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