Verma Aryan, Amin Sagar B, Naeem Muhammad, Saha Monjoy
Department of Computer Science and Engineering, National Institute of Technology, Hamirpur, HP, 177005, India.
Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Comput Biol Med. 2022 Apr;143:105298. doi: 10.1016/j.compbiomed.2022.105298. Epub 2022 Feb 20.
The COVID-19 (coronavirus disease 2019) pandemic affected more than 186 million people with over 4 million deaths worldwide by June 2021. The magnitude of which has strained global healthcare systems. Chest Computed Tomography (CT) scans have a potential role in the diagnosis and prognostication of COVID-19. Designing a diagnostic system, which is cost-efficient and convenient to operate on resource-constrained devices like mobile phones would enhance the clinical usage of chest CT scans and provide swift, mobile, and accessible diagnostic capabilities. This work proposes developing a novel Android application that detects COVID-19 infection from chest CT scans using a highly efficient and accurate deep learning algorithm. It further creates an attention heatmap, augmented on the segmented lung parenchyma region in the chest CT scans which shows the regions of infection in the lungs through an algorithm developed as a part of this work, and verified through radiologists. We propose a novel selection approach combined with multi-threading for a faster generation of heatmaps on a Mobile Device, which reduces the processing time by about 93%. The neural network trained to detect COVID-19 in this work is tested with a F1 score and accuracy, both of 99.58% and sensitivity of 99.69%, which is better than most of the results in the domain of COVID diagnosis from CT scans. This work will be beneficial in high-volume practices and help doctors triage patients for the early diagnosis of COVID-19 quickly and efficiently.
到2021年6月,新冠疫情(2019冠状病毒病)已影响全球超过1.86亿人,导致400多万人死亡。其规模给全球医疗系统带来了压力。胸部计算机断层扫描(CT)在新冠诊断和预后评估中具有潜在作用。设计一种经济高效且便于在手机等资源受限设备上操作的诊断系统,将提高胸部CT扫描的临床应用,并提供快速、移动且可及的诊断能力。这项工作提出开发一种新型安卓应用程序,该程序使用高效准确的深度学习算法从胸部CT扫描中检测新冠感染。它还会创建一个注意力热图,叠加在胸部CT扫描中分割出的肺实质区域上,通过作为这项工作一部分开发并经放射科医生验证的算法显示肺部的感染区域。我们提出一种结合多线程的新颖选择方法,以便在移动设备上更快地生成热图,这将处理时间减少了约93%。在这项工作中训练用于检测新冠的神经网络,F1分数和准确率均为99.58%,灵敏度为99.69%,优于CT扫描新冠诊断领域的大多数结果。这项工作将有利于大规模实践,并帮助医生快速有效地对患者进行分诊,以便早期诊断新冠。