Antimalarial drug resistance in tropical countries: a solution towards decreasing mortality of children under 5 years of age.
作者信息
Sadiq Idris Zubairu
机构信息
Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
出版信息
Sudan J Paediatr. 2021;21(2):228-231. doi: 10.24911/SJP.106-1617926256.
Abstract
摘要
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Sudan J Paediatr. 2021;21(2):228-231. doi: 10.24911/SJP.106-1617926256.
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本文引用的文献
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Knowing the enemy: genetics to track antimalarial resistance.了解敌人：利用遗传学追踪抗疟药物耐药性
Lancet Infect Dis. 2020 Dec;20(12):1361-1362. doi: 10.1016/S1473-3099(20)30271-1. Epub 2020 Jul 14.
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Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria.中非、西非和东非重症疟疾儿童抗疟药物耐药性的分子标志物
Malar J. 2017 May 23;16(1):217. doi: 10.1186/s12936-017-1868-y.
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Severe Malaria in African Children - The Need for Continuing Investment.非洲儿童的重症疟疾——持续投资的必要性
N Engl J Med. 2016 Dec 22;375(25):2416-2417. doi: 10.1056/NEJMp1613528.
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Artemisinin Resistance in Southeast Asia.东南亚的青蒿素耐药性。
Clin Infect Dis. 2016 Dec 1;63(11):1527. doi: 10.1093/cid/ciw583. Epub 2016 Aug 23.
5
Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children.抗疟治疗和化学预防对从乌干达儿童分离出的疟原虫药物敏感性的影响。
Antimicrob Agents Chemother. 2015;59(6):3018-30. doi: 10.1128/AAC.05141-14. Epub 2015 Mar 9.
6
Plasmodium falciparum drug resistance phenotype as assessed by patient antimalarial drug levels and its association with pfmdr1 polymorphisms.恶性疟原虫药物耐药表型的评估方法为检测患者抗疟药物水平及其与 pfmdr1 多态性的关系。
J Infect Dis. 2013 Mar 1;207(5):842-7. doi: 10.1093/infdis/jis747. Epub 2012 Dec 5.
7
In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.在肯尼亚恶性疟原虫分离株中哌喹、青蒿琥酯和二氢青蒿素的体外活性以及 pfcrt 和 pfmdr1 的多态性。
Antimicrob Agents Chemother. 2009 Dec;53(12):5069-73. doi: 10.1128/AAC.00638-09. Epub 2009 Sep 21.
8
Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum.恶性疟原虫的pfmdr1基因突变会导致对疟疾药物甲氟喹和青蒿素的敏感性增加。
Mol Microbiol. 2000 May;36(4):955-61. doi: 10.1046/j.1365-2958.2000.01914.x.
9
The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin.恶性疟原虫pfmdr1基因的酪氨酸86等位基因与对抗疟药甲氟喹和青蒿素的敏感性增加有关。
Mol Biochem Parasitol. 2000 Apr 30;108(1):13-23. doi: 10.1016/s0166-6851(00)00201-2.
10
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum.Pgh1调节恶性疟原虫对多种抗疟药物的敏感性和耐药性。
Nature. 2000 Feb 24;403(6772):906-9. doi: 10.1038/35002615.
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