Emerg Infect Dis. 2017 Dec;23(13):S53-6. doi: 10.3201/eid2313.170366.
Antimalarial drug resistance is an evolving global health security threat to malaria control. Early detection of Plasmodium falciparum resistance through therapeutic efficacy studies and associated genetic analyses may facilitate timely implementation of intervention strategies. The US President's Malaria Initiative-supported Antimalarial Resistance Monitoring in Africa Network has assisted numerous laboratories in partner countries in acquiring the knowledge and capability to independently monitor for molecular markers of antimalarial drug resistance.
抗疟药耐药性是对疟疾控制构成的不断演变的全球卫生安全威胁。通过治疗效果研究和相关遗传分析尽早发现恶性疟原虫的耐药性,可能有助于及时实施干预策略。美国总统疟疾倡议支持的非洲抗疟药耐药性监测网络协助了伙伴国家的许多实验室获得了独立监测抗疟药耐药性分子标记的知识和能力。