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肝内胆管癌的微创手术:患者选择与特殊考量

Minimally Invasive Surgery for Intrahepatic Cholangiocarcinoma: Patient Selection and Special Considerations.

作者信息

Owen MacKenzie L, Beal Eliza W

机构信息

The Ohio State University College of Medicine, Columbus, OH, USA.

The Ohio State University Comprehensive Cancer Center, Department of Surgery, Division of Surgical Oncology, Columbus, OH, USA.

出版信息

Hepat Med. 2021 Dec 22;13:137-143. doi: 10.2147/HMER.S319027. eCollection 2021.

Abstract

Intrahepatic cholangiocarcinoma (ICC) is an aggressive primary hepatic malignancy. Unfortunately, despite advancements in diagnosis, staging and management, mortality is high. Surgery remains the only curative treatment, but many patients present with advanced, unresectable disease. For patients able to undergo surgical resection, overall survival is improved, but remains low, with high rates of disease recurrence. Minimally invasive surgery (MIS), including laparoscopic and robotic approaches, are increasingly used in surgical resection for ICC. These approaches variably demonstrate faster recovery times, less blood loss, decreased postoperative pain and fewer postoperative complications, with adequate oncologic resections. This review examines patient selection and special considerations for MIS for ICC. Patient selection is critical and includes evaluation of a patient's anatomic and oncologic resectability, as well as comorbidities.

摘要

肝内胆管癌(ICC)是一种侵袭性原发性肝脏恶性肿瘤。不幸的是,尽管在诊断、分期和治疗方面取得了进展,但死亡率仍然很高。手术仍然是唯一的治愈性治疗方法,但许多患者就诊时已处于晚期、无法切除的疾病状态。对于能够接受手术切除的患者,总生存率有所提高,但仍然较低,疾病复发率很高。包括腹腔镜和机器人手术在内的微创手术(MIS)越来越多地用于ICC的手术切除。这些手术方式在进行充分的肿瘤切除时,不同程度地显示出恢复时间更快、失血更少、术后疼痛减轻以及术后并发症更少。本综述探讨了ICC患者选择和MIS的特殊注意事项。患者选择至关重要,包括评估患者的解剖学和肿瘤可切除性以及合并症。

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