Eum Yoon Hee, Kim Ho Jun, Bak Seolah, Lee Sung-Ha, Kim Jinri, Park Su Hyeon, Hwang Seo Eun, Oh Bumjo
Department of Family Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
Department of Family Medicine, Hongseong Medical Center, Chungcheongnam-do, Republic of Korea.
Tob Induc Dis. 2022 Feb 8;20:15. doi: 10.18332/tid/144272. eCollection 2022.
Every year, at least half of the smokers in South Korea attempt to quit smoking. However, the Korean smoking rate remains still high among OECD countries. This study aimed to identify the factors that influence the success of smoking cessation efforts.
The study included 1395 smokers, who participated in a 12-week program comprising doctor counseling and pharmacological treatment (i.e. varenicline), conducted at smoking cessation clinics in two general hospitals from 2015 to 2019. The participants responded to a survey questionnaire inquiring about their smoking behaviors at the first visit to the clinic. After completing the program, they were asked whether they succeeded in smoking cessation. Based on participants' reported success or failure, multivariable logistic regression analyses were conducted to obtain adjusted odds ratios (AORs) and 95% confidence intervals (CIs) for factors related to smoking cessation success.
Following the 12-week program, 39.6% of the participants (n=553) succeeded in smoking cessation. Lower rates of nicotine dependence (AOR=0.73; 95% Cl: 0.54-0.98) and lower total amounts of smoking (AOR=0.67; 95% Cl: 0.47-0.95) were significantly associated with higher success rates in smoking cessation. In addition, smokers who participated in the program for at least 8 weeks (AOR=7.16; 95% Cl: 5.57-9.20) and smokers who had hypertension (AOR=1.40; 95% Cl: 1.07-1.85) or a cardiovascular disease (AOR=1.68; 95% Cl: 1.03-2.75) achieved higher success rates.
Smokers' success in smoking cessation was influenced by the period of visits to the smoking cessation clinic, the severity of nicotine dependence, and the presence of a cardiovascular disease including hypertension. Using these factors, smoking cessation strategy may be improved and personalized for individuals.
每年，韩国至少一半的吸烟者试图戒烟。然而，在经合组织国家中，韩国的吸烟率仍然很高。本研究旨在确定影响戒烟努力成功的因素。
该研究纳入了1395名吸烟者，他们于2015年至2019年在两家综合医院的戒烟诊所参加了一个为期12周的项目，该项目包括医生咨询和药物治疗（即伐尼克兰）。参与者在首次就诊时回答了一份关于其吸烟行为的调查问卷。完成该项目后，询问他们是否成功戒烟。根据参与者报告的成功或失败情况，进行多变量逻辑回归分析，以获得与戒烟成功相关因素的调整优势比（AOR）和95%置信区间（CI）。
经过12周的项目，39.6%的参与者（n = 553）成功戒烟。较低的尼古丁依赖率（AOR = 0.73；95%CI：0.54 - 0.98）和较低的总吸烟量（AOR = 0.67；95%CI：0.47 - 0.95）与较高的戒烟成功率显著相关。此外，参加该项目至少8周的吸烟者（AOR = 7.16；95%CI：5.57 - 9.20）以及患有高血压（AOR = 1.40；95%CI：1.07 - 1.85）或心血管疾病（AOR = 1.68；95%CI：1.03 - 2.75）的吸烟者成功率更高。
吸烟者的戒烟成功受到到戒烟诊所就诊的时长、尼古丁依赖的严重程度以及包括高血压在内的心血管疾病的影响。利用这些因素，戒烟策略可能会得到改善并实现个性化。
