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[具有抗真菌活性的N-吡唑基-2-硝基苯甲酰胺]

[N-pyrazolyl-2-nitrobenzamides with antifungal activity].

作者信息

Daidone G, Plescia S, Raffa D, Sprio V, Milici M

出版信息

Farmaco Sci. 1986 May;41(5):408-16. doi: 10.1002/chin.198646220.

Abstract

Novel N-pyrazolyl-2-nitrobenzamides variously substituted on the pyrazole nucleus were prepared. The products obtained together with some other N-substituted 2-nitrobenzamides were tested for their antifungal activity against Cryptococcus neoformans and Candida albicans. The results of the antimicrobial assay showed different behaviours of the organisms used with regard to the derivatives tested.

摘要

制备了在吡唑核上有不同取代基的新型N-吡唑基-2-硝基苯甲酰胺。将得到的产物与其他一些N-取代的2-硝基苯甲酰胺一起测试了它们对新型隐球菌和白色念珠菌的抗真菌活性。抗菌试验结果表明,所用微生物对所测试的衍生物表现出不同的行为。

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