Prathipati Kiran Kumar, Mishra Meena, Rathod Bharatsing, Tripathy Jaya P, B H Shrikrishna, Bidkar Vijay, Dabhekar Sandeep, Shete Vishal, G Deepa
Ear, Nose, and Throat, All India Institute of Medical Sciences, Nagpur, IND.
Microbiology, All India Institute of Medical Sciences, Nagpur, IND.
Cureus. 2022 Jan 24;14(1):e21541. doi: 10.7759/cureus.21541. eCollection 2022 Jan.
The COVID-19 pandemic has affected the world population across the globe. India has the secondlargest number of cases and the thirdlargest number of deaths due to COVID-19 in the world. There have been close to 4.4 lakh deaths due to COVID-19 in India alone. The second wave in India has led to devastating consequences, particularly among the young population. The initial clinical symptoms of COVID-19 are similar to all types of viral pneumonia, with varying degrees of severity. The cases' clinical manifestations include fever, nonproductive cough, dyspnea, myalgia, and fatigue. This study was undertaken with the purpose of identifying the relationship between the symptoms and duration in COVID-19-affected patients. The common presenting symptoms were fever (44.5%), sore throat (38.7%), and cough (36.12%). Most of the cases presented with a combination of fever with cough (35%) and fever with sore throat (33%). The duration of symptoms varied from one to 17 days with a mean of 5.75 days. Despite vaccination being started, the risk of the imminent third wave in the country is existential. Mutations in the coronavirus pose a threat to the vulnerable population. It is important to identify the combination of symptoms most predictive of COVID-19 to help guide recommendations for self-isolation, testing, and preventing further spread of the disease. Further studies using these models can yield better results in surveillance and containing this infectious disease.
新冠疫情已影响到全球各地的人口。印度的新冠病例数位居世界第二，死亡人数位居世界第三。仅在印度，因新冠疫情导致的死亡人数就接近44万。印度的第二波疫情造成了毁灭性后果，尤其是在年轻人群体中。新冠疫情的初始临床症状与所有类型的病毒性肺炎相似，严重程度各不相同。病例的临床表现包括发热、干咳、呼吸困难、肌痛和疲劳。本研究旨在确定新冠感染患者症状与病程之间的关系。常见的症状表现为发热（44.5%）、喉咙痛（38.7%）和咳嗽（36.12%）。大多数病例表现为发热伴咳嗽（35%）和发热伴喉咙痛（33%）。症状持续时间从1天到17天不等，平均为5.75天。尽管已经开始接种疫苗，但该国即将到来的第三波疫情风险依然存在。冠状病毒的变异对弱势群体构成威胁。确定最能预测新冠的症状组合，对于指导自我隔离、检测及预防疾病进一步传播的建议非常重要。使用这些模型的进一步研究可以在监测和控制这种传染病方面取得更好的效果。
