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病例报告:肺炎球菌慢性无菌性脑膜炎后脑脊液中肺炎球菌多糖持续存在:偶然现象还是(自身)炎症余烬。

Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers.

作者信息

Ladeveze Manon, Dumont Yann, Boursier G, Batteux Frederic, Mahe Perrine, Bensimon Borrull Aurelie, Sarrabay Guillaume, Bollore Karine, Tuaillon Edouard, Godreuil Sylvain, Jeziorski Eric

机构信息

Département Urgences Post-Urgences, CEREMAIA, CHU de Montpellier, Montpellier, France.

Laboratoire de Bactériologie, CHU de Montpellier, Montpellier, France.

出版信息

Front Pediatr. 2022 Feb 9;10:762457. doi: 10.3389/fped.2022.762457. eCollection 2022.

Abstract

We report the case of a 9-months-old boy that has presented a steroid-dependent post-pneumococcal chronic aseptic meningitis was associated with persistence of pneumococcal cell wall components in cerebrospinal fluid during more than 20 months. Suggesting that this antigenic persistence could be involved in post-infectious manifestations through innate immunity response.

摘要

我们报告了一例9个月大的男孩,他患有类固醇依赖型肺炎球菌感染后慢性无菌性脑膜炎,脑脊液中肺炎球菌细胞壁成分持续存在超过20个月。这表明这种抗原持续存在可能通过先天免疫反应参与感染后的表现。

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