Garcia Juan F, Diez M Jose, Sahagun Ana M, Diez Raquel, Sierra Matilde, Garcia Juan J, López Cristina, Fernandez M Nelida
Department of Mechanical, Informatics and Aerospatiale Engineering, University of Leon, Leon, Spain.
Department of Biomedical Sciences, Institute of Biomedicine (IBIOMED), Veterinary Faculty, University of Leon, Leon, Spain.
Front Vet Sci. 2022 Feb 11;8:798850. doi: 10.3389/fvets.2021.798850. eCollection 2021.
The misuse or overuse of antibiotics can favor the emergence of antimicrobial resistance, with a direct impact on human and animal health as well as on ecosystems. In this work, we have analyzed the web pages in which antibiotics for veterinary use can be purchased online. By using a specifically developed software, we carried out a detailed search to know if each individual antibiotic and the families included in the OIE list of antimicrobial agents of veterinary importance (in English and in Spanish) were sold, reviewing the offers according to the administration route and the species for which the antibiotics were intended. The greatest offer of antibiotics was for those compounds considered critically important by OIE. In the search in English, penicillins were available on 55.8% of the sites, tetracyclines on 55.0%, and fluoroquinolones on 52.7%. In Spanish, the families with the greatest presence were fluoroquinolones (67.9% of the sites), tetracyclines (67.9% of the sites), and penicillins (65.4% of the sites). Regarding individual antibiotics, the most offered in both searches were amoxicillin (49.6% of the sites in English and 57.7% in Spanish) and doxycycline (46.5% of the sites in English and 53.8% in Spanish). Most offers were for oral and parenteral administration and intended for cats and dogs and for bovines.
抗生素的滥用或过度使用会助长抗菌药物耐药性的出现,对人类、动物健康以及生态系统产生直接影响。在这项研究中,我们分析了可在线购买兽用抗生素的网页。通过使用专门开发的软件,我们进行了详细搜索,以了解是否售卖了每一种单独的抗生素以及世界动物卫生组织(OIE)兽医重要抗菌剂清单中所列的各类抗生素(英文和西班牙文),并根据给药途径和抗生素适用的物种对相关销售信息进行了审查。售卖最多的抗生素是那些被OIE视为极为重要的化合物。在英文搜索中,55.8%的网站有青霉素出售,55.0%的网站有四环素出售,52.7%的网站有氟喹诺酮类出售。在西班牙文搜索中,出现频率最高的类别是氟喹诺酮类(占网站的67.9%)、四环素类(占网站的67.9%)和青霉素类(占网站的65.4%)。关于单一抗生素,在两次搜索中售卖最多的都是阿莫西林(英文搜索中占网站的49.6%,西班牙文搜索中占57.7%)和强力霉素(英文搜索中占网站的46.5%,西班牙文搜索中占53.8%)。大多数销售信息针对口服和注射给药,适用对象为猫、狗和牛。