Luz Romero Rosa María, Illán Ramos Marta, Berzosa Sánchez Arantxa, Joyanes Abancens Belén, Baos Muñoz Elvira, Ramos Amador José Tomás
Servicio de Pediatría, Hospital Clínico San Carlos, Madrid, Spain.
Servicio de Microbiología Clínica, Hospital Clínico San Carlos, Madrid, Spain.
Med Clin (Engl Ed). 2022 Apr 8;158(7):336-339. doi: 10.1016/j.medcle.2021.11.004. Epub 2022 Feb 21.
Most SARS-CoV2 infections in the pediatric population are asymptomatic or with mild symptoms, with a minimal proportion of severe cases described as SARS-CoV2-associated multi-system inflammatory syndrome (MIS-C).The objective was to describe the clinical and epidemiological characteristics of pediatric patients admitted with confirmed diagnosis of SARS-CoV2 infection from the beginning of the pandemic until May 2021.
Retrospective observational study of pediatric patients hospitalized with confirmed COVID-19, in a tertiary hospital. Epidemiological and clinical data, additional tests, treatments administered and evolution were collected.
30 patients were included, classified into 3 groups according to diagnosis: respiratory infection, MIS-C and compatible symptoms. The patients with pneumonia were associated with age older, comorbidities and lymphopenia. MIS-C were more serious patients, with marked laboratory involvement and greater admission to PICU. Most of these were secondary cases of contact in the family environment.
The most frequent clinical manifestations of COVID-19 in children are mild-moderate respiratory with good evolution. MIS-C is another form of expression of SARS-COV2 infection of greater severity, but usually with good prognosis after early diagnosis and frequent PICU admission.
儿科人群中大多数新冠病毒感染无症状或症状轻微,被描述为与新冠病毒相关的多系统炎症综合征(MIS-C)的重症病例比例极低。目的是描述自大流行开始至2021年5月期间确诊感染新冠病毒的儿科患者的临床和流行病学特征。
在一家三级医院对确诊感染新冠病毒的住院儿科患者进行回顾性观察研究。收集了流行病学和临床数据、额外检查、所给予的治疗及病情演变情况。
纳入30例患者,根据诊断分为3组:呼吸道感染、MIS-C和症状相符组。肺炎患者与年龄较大、合并症及淋巴细胞减少有关。MIS-C患者病情更严重,实验室指标明显受累,入住儿科重症监护病房(PICU)的比例更高。其中大多数是家庭环境中的二代接触病例。
儿童新冠病毒感染最常见的临床表现是轻至中度呼吸道症状,病情进展良好。MIS-C是新冠病毒感染的另一种更严重的表现形式,但早期诊断并频繁入住PICU后通常预后良好。