• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

因新型冠状病毒肺炎住院儿童的临床特征。

Clinical characteristics of children hospitalized for COVID-19.

作者信息

Luz Romero Rosa María, Illán Ramos Marta, Berzosa Sánchez Arantxa, Joyanes Abancens Belén, Baos Muñoz Elvira, Ramos Amador José Tomás

机构信息

Servicio de Pediatría, Hospital Clínico San Carlos, Madrid, Spain.

Servicio de Microbiología Clínica, Hospital Clínico San Carlos, Madrid, Spain.

出版信息

Med Clin (Engl Ed). 2022 Apr 8;158(7):336-339. doi: 10.1016/j.medcle.2021.11.004. Epub 2022 Feb 21.

DOI:10.1016/j.medcle.2021.11.004
PMID:35224201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8858688/
Abstract

INTRODUCTION

Most SARS-CoV2 infections in the pediatric population are asymptomatic or with mild symptoms, with a minimal proportion of severe cases described as SARS-CoV2-associated multi-system inflammatory syndrome (MIS-C).The objective was to describe the clinical and epidemiological characteristics of pediatric patients admitted with confirmed diagnosis of SARS-CoV2 infection from the beginning of the pandemic until May 2021.

METHODS

Retrospective observational study of pediatric patients hospitalized with confirmed COVID-19, in a tertiary hospital. Epidemiological and clinical data, additional tests, treatments administered and evolution were collected.

RESULTS

30 patients were included, classified into 3 groups according to diagnosis: respiratory infection, MIS-C and compatible symptoms. The patients with pneumonia were associated with age older, comorbidities and lymphopenia. MIS-C were more serious patients, with marked laboratory involvement and greater admission to PICU. Most of these were secondary cases of contact in the family environment.

DISCUSSION

The most frequent clinical manifestations of COVID-19 in children are mild-moderate respiratory with good evolution. MIS-C is another form of expression of SARS-COV2 infection of greater severity, but usually with good prognosis after early diagnosis and frequent PICU admission.

摘要

引言

儿科人群中大多数新冠病毒感染无症状或症状轻微,被描述为与新冠病毒相关的多系统炎症综合征(MIS-C)的重症病例比例极低。目的是描述自大流行开始至2021年5月期间确诊感染新冠病毒的儿科患者的临床和流行病学特征。

方法

在一家三级医院对确诊感染新冠病毒的住院儿科患者进行回顾性观察研究。收集了流行病学和临床数据、额外检查、所给予的治疗及病情演变情况。

结果

纳入30例患者,根据诊断分为3组:呼吸道感染、MIS-C和症状相符组。肺炎患者与年龄较大、合并症及淋巴细胞减少有关。MIS-C患者病情更严重,实验室指标明显受累,入住儿科重症监护病房(PICU)的比例更高。其中大多数是家庭环境中的二代接触病例。

讨论

儿童新冠病毒感染最常见的临床表现是轻至中度呼吸道症状,病情进展良好。MIS-C是新冠病毒感染的另一种更严重的表现形式,但早期诊断并频繁入住PICU后通常预后良好。

相似文献

1
Clinical characteristics of children hospitalized for COVID-19.因新型冠状病毒肺炎住院儿童的临床特征。
Med Clin (Engl Ed). 2022 Apr 8;158(7):336-339. doi: 10.1016/j.medcle.2021.11.004. Epub 2022 Feb 21.
2
Clinical characteristics of children hospitalized for COVID-19.儿童 COVID-19 住院患者的临床特征。
Med Clin (Barc). 2022 Apr 8;158(7):336-339. doi: 10.1016/j.medcli.2021.11.016. Epub 2021 Dec 28.
3
Characteristics and management of patients with SARS-CoV2 infection admitted to pediatric intensive care units: Data analysis of the Spanish national multicenter registry.因 SARS-CoV2 感染而入住儿科重症监护病房的患者的特征和管理:西班牙全国多中心登记处的数据分析。
Pediatr Pulmonol. 2023 Oct;58(10):2916-2929. doi: 10.1002/ppul.26613. Epub 2023 Jul 26.
4
COVID-19 Disease in Presenting to the Pediatric Emergency Department: A Multicenter Study of 8886 Cases.COVID-19 疾病在儿科急诊科的表现:一项 8886 例病例的多中心研究。
Am J Emerg Med. 2022 Sep;59:133-140. doi: 10.1016/j.ajem.2022.06.015. Epub 2022 Jun 9.
5
Severe manifestations of SARS-CoV-2 in children and adolescents: from COVID-19 pneumonia to multisystem inflammatory syndrome: a multicentre study in pediatric intensive care units in Spain.儿童和青少年中严重的 SARS-CoV-2 表现:从 COVID-19 肺炎到多系统炎症综合征:西班牙儿科重症监护病房的一项多中心研究。
Crit Care. 2020 Nov 26;24(1):666. doi: 10.1186/s13054-020-03332-4.
6
Clinical spectrum of COVID-19 and risk factors associated with severity in Spanish children.COVID-19 的临床特征及与西班牙儿童严重程度相关的危险因素
Eur J Pediatr. 2022 Mar;181(3):1105-1115. doi: 10.1007/s00431-021-04306-6. Epub 2021 Nov 5.
7
Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19: A Case Series Experience in a Tertiary Care Hospital of Southern Turkey.儿童多系统炎症综合征(MIS-C)与 COVID-19 相关:土耳其南部一家三级保健医院的病例系列经验。
J Trop Pediatr. 2021 May 17;67(2). doi: 10.1093/tropej/fmab050.
8
A Comparative Study of Children with MIS-C between Admitted to the Pediatric Intensive Care Unit and Pediatric Ward: A One-Year Retrospective Study.儿童川崎病合并巨噬细胞活化综合征患儿在重症监护病房与普通病房住院的比较研究:一项为期一年的回顾性研究。
J Trop Pediatr. 2021 Dec 8;67(6). doi: 10.1093/tropej/fmab104.
9
Testing the efficacy and safety of BIO101, for the prevention of respiratory deterioration, in patients with COVID-19 pneumonia (COVA study): a structured summary of a study protocol for a randomised controlled trial.评估 BIO101 预防 COVID-19 肺炎患者呼吸恶化的疗效和安全性(COVA 研究):一项随机对照试验研究方案的结构化总结。
Trials. 2021 Jan 11;22(1):42. doi: 10.1186/s13063-020-04998-5.
10
The Spectrum of Manifestations of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV2) Infection in Children: What We Can Learn From Multisystem Inflammatory Syndrome in Children (MIS-C).严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染在儿童中的表现谱:我们能从儿童多系统炎症综合征(MIS-C)中学到什么。
Front Med (Lausanne). 2021 Oct 28;8:747190. doi: 10.3389/fmed.2021.747190. eCollection 2021.

引用本文的文献

1
Challenges of the Implementation of a Delirium Rate Scale in a Pediatric Intensive Care Unit: A Qualitative Approach.儿科重症监护病房实施谵妄率量表的挑战:一种定性研究方法
Healthcare (Basel). 2023 Dec 26;12(1):52. doi: 10.3390/healthcare12010052.

本文引用的文献

1
Cardiovascular impact of COVID-19 with a focus on children: A systematic review.新冠病毒病对心血管系统的影响(聚焦于儿童):一项系统综述
World J Clin Cases. 2020 Nov 6;8(21):5250-5283. doi: 10.12998/wjcc.v8.i21.5250.
2
[Spanish consensus document on diagnosis, stabilisation and treatment of pediatric multisystem inflammatory syndrome related to SARS-CoV-2 (SIM-PedS)].[关于与SARS-CoV-2相关的儿童多系统炎症综合征(SIM-PedS)的诊断、稳定和治疗的西班牙共识文件]
An Pediatr (Engl Ed). 2021 Feb;94(2):116.e1-116.e11. doi: 10.1016/j.anpedi.2020.09.005. Epub 2020 Oct 31.
3
Clinical spectrum and risk factors for complicated disease course in children admitted with SARS-CoV-2 infection.2019冠状病毒病感染患儿复杂病程的临床谱及危险因素
An Pediatr (Engl Ed). 2020 Nov;93(5):323-333. doi: 10.1016/j.anpede.2020.07.005. Epub 2020 Oct 15.
4
A systematic review and meta-analysis of children with coronavirus disease 2019 (COVID-19).一项关于儿童 2019 冠状病毒病(COVID-19)的系统评价和荟萃分析。
J Med Virol. 2021 Feb;93(2):1057-1069. doi: 10.1002/jmv.26398. Epub 2020 Sep 28.
5
Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2.58 例与 SARS-CoV-2 相关的儿童炎症性多系统综合征的临床特征。
JAMA. 2020 Jul 21;324(3):259-269. doi: 10.1001/jama.2020.10369.
6
Acute Heart Failure in Multisystem Inflammatory Syndrome in Children in the Context of Global SARS-CoV-2 Pandemic.儿童多系统炎症综合征伴发急性心力衰竭:全球 SARS-CoV-2 大流行背景下的临床观察
Circulation. 2020 Aug 4;142(5):429-436. doi: 10.1161/CIRCULATIONAHA.120.048360. Epub 2020 May 17.
7
Coronavirus Disease 2019 in Children - United States, February 12-April 2, 2020.2019 年冠状病毒病在儿童中的情况-美国,2020 年 2 月 12 日至 4 月 2 日。
MMWR Morb Mortal Wkly Rep. 2020 Apr 10;69(14):422-426. doi: 10.15585/mmwr.mm6914e4.
8
SARS-CoV-2 Infection in Children.儿童感染新型冠状病毒2型
N Engl J Med. 2020 Apr 23;382(17):1663-1665. doi: 10.1056/NEJMc2005073. Epub 2020 Mar 18.